صاحب يحيى حسن المرشدي

ABSTRACT Background: Assisted reproduction is a complicated process involving multiple stage of ovarian stimulation, ovum pick-up, fertilization, embryo cleavage and implantation. The goal of all these procedures is achievement of viable intrauterine pregnancy as a step of achievement of healthy baby. Aim: The aim of the current study was to find out possible effect of body mass index on serum inhibin levels, and at the end on the fade of intracytoplasmic sperm injection outcome in women. In addition, the present study evaluate the rate of pregnancy in association with BMI either obese, overweight and normal. Methods: This prospective study was performed in the fertility center and urology center at AL-Sader medical city in AL-Najaf governorate involving(150) female participate in this study between November 2015 and June 2016. Results: Present study demonstrated that obese women who are subfertile were undergoing ICSI procedure are prone to have lower pregnancy rate in comparison to normal one. While, there is no significant correlation between categorized groups of women regarding BMI and inhibin B in serum measure at second day of cycle and follicular inhibin B at ovum pickup. Inhibin B is less sensitive to BMI. Conclusion: Finally, present study concluded that age of women is important factor affecting the outcomes of ICSI, in women age >35 years old had

Background: infertile couples due to male factor reasons present with azoospermia as a cause of their infertility can positively benefit from intracytoplasmic sperm injection (ICSI) for fathering genetics offspring's. Aim of study: to compare the intracytoplasmic sperm injection outcomes in obstructive and non-obstructive azoospermic men. Materials and methods: A retrospective study compromised 42 couples seeking for treatment due to azoospermia as a cause of infertility. 19 men out of 42 had obstructive azoospermia (OA) and the remainder 23 man had non-obstructive azoospermia (NOA). All those males underwent surgical sperm retrieval techniques either testicular sperm extraction (TESE) in all NOA cases and some OA cases or percutaneous epididymal sperm aspiration (PESA) in the rest of OA cases. Sperms retrieved surgically were used either fresh or after cryopreservation for ICSI and the main outcomes; fertilization, cleavage and pregnancy rates and embryo quality were compared statistically. Data were expressed as mean ±SD and number and percent, and groups were compared by compares of two independent means. Dif-ferences were considered significant at p <0.05. Results: the results revealed significant reduction (p <0.05) in the fertilization rate in couples with NOA (38.2%) compare to (59.5%) for OA group, as well as a significant drop in cleavage (80.6% vs 68.9%) and pregnancy (31.57% vs 13.04%) rates was also shown in NOA group. The mean number of embryos (5.88±3.46 vs 3.33±2.54, p <0.017) obtained by ICSI and percent of good quality embryos (55.2% vs 31.37%, p <0.014) were significantly higher in OA group. Conclusion: type of azoospermia has greater effect on the success of ICSI cycles. The immaturity of testicular sperm in NOA can affect fertilization, embryo development and pregnancy rate

Abstract The study was included examination of (30) samples for normozoospermic , oligozoospermic and azoospermic men . This research was aimed to find best method of semen volume measurement by graduated tubes or weighing as well as to determination the sperm percent of normozoospermic and oligozoospermic men . This work was included weight one ml of semen . The result was revealed nonsignificantly difference (p > 0.05) between semen weight (1 ml) of for normozoospermic , oligozoospermic and azoospermic men ,while the result was showed significant increase (p < 0.05) of semen volume by weighing compared with graduated tubes . In conclusion , the presence of sperm does not significantly influence of the result so semen volume is best measured by weighing the sample in the collection vessel rather than decanting the semen into graduated tubes,. because losses of semen during decanting semen into graduted tubes