مواقع التدريسيينجامعة الكوفة
كوثر عدنان حسن القصير
أستاذ مساعد

كوثر عدنان حسن القصير

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الملف الشخصي

اكملت دراسة الماجستير في اختصاص الاحياء المجهرية /بكتريا مرضية في كليه العلوم /جامعة الكوفه ثم اكملت دراسة الدكتوراه في جامعة لستر في بريطانيا بنفس الاختصاص.
مهتمه في كل مايتعلق بالتركيب الجيني للبكتريا واحداث الطفرات الوراثيه كما مهتمه ايضا بدراسة التركيب البروتيني للبكتريا.

الاهتمامات البحثية

1

البحوث المنشورة

11
2023/3/27

Identification and characterization of a novel lytic peptidoglycan transglycosylase (MltC) in Shigella dysenteriae

الباحثونBaleegh A Kadhim، Kawther Alqaseer, Sura A Al-Ganahi
المجلةBrazilian Journal of Microbiology
مختصر البحث

Shigellosis remains a worldwide health problem due to the lack of vaccines and the emergence of antibiotic-resistant strains. Shigella (S.) dysenteriae has rigid peptidoglycan (PG), and its tight regulation of biosynthesis and remodeling is essential for bacterial integrity. Lytic transglycosylases are highly conserved PG autolysins in bacteria that play essential roles in bacterial growth. However, their precise functions are obscure. We aimed to identify, clone, and express MltC, a unique autolysin in Escherichia (E.) coli C41 strain. The purification of recombinant MltC protein was performed using affinity chromatography and size-exclusion chromatography methods. The PG enzymatic activity of MltC was investigated using Zymogram and Fluorescein isothiocyanate (FITC)-labeled PG assays. Also, we aimed to detect its localization in bacterial fractions (cytoplasm and membrane) by western blot using specific polyclonal

2023/3/26

Selenium nanoparticles inhibit Staphylococcus aureus-induced nosocomial infection, cell death and biofilm formation

الباحثونOhood A Radhi، Intisar Albandar, Kawther Alqaseer, Wijdan D Shnain
المجلة The JOURNAL OF POPULATION THERAPEUTICS AND CLINICAL PHARMACOLOGY
مختصر البحث

Background: Staphylococcus aureus that is a major health problem in hospitals, recognized as the greatest important nosocomial pathogen and usually causing postoperative wound infections. Antibiotic resistance by Staphylococcus aureus has developed to be common, and resistance to almost all antibiotics has been found among the most strains of this pathogen. Biofilms are generally more resistant to both host’s defense mechanisms and to antibiotics than planktonic unicellular microbes. Therefore, it is increasingly recognized as important health problem for patients with microbial infections. Moreover, Staphylococcal diseases has found to be connected with programmed cell death in order to cause numerous diseases in human hosts. All that made Staphylococcus aureus infections are hard to treat. Selenium has been examined for numerous medical applications and evidence suggested that Staphylococcus aureus growth can be inhibited in the presence of selenium nanoparticles. Objectives: The specific objective of this study therefore was to investigate the prevalence, antimicrobial susceptibility patterns and associated risk factors of Staphylococcus aureus in patients with surgical site infections and burns infection. In addition to confirm that selenium nanoparticles may be used to effectively prevent and treat Staphylococcus aureus infections and thus should be further studied for such applications. Methods: A cross-sectional study was conducted from January 1, 2022 to December 30, 2022 among patients with surgical site infections and burns infection at Al- Najaf city hospitals in Iraq country. A total of 275 Staphylococcus aureus isolates were recovered from hospital patients with postoperative wound infection or burns infection isolation and identification were based on standard bacteriological and biochemical criteria. Biofilms formation in vitro was carried out by microtiter plate spectrophotometric technique. Through using the standard disc diffusion technique, isolated strains of Staphylococcus aureus were tested for antibiotic susceptibility patterns. Host cell killing by Staphylococcus aureus was assayed by using florescent microscopy. Finally, selenium nanoparticles to inhibit bacteria were tested by measuring the sizes of the inhibition zone for bacterial growth.

2023

Community-Associated Methicillin-Resistant Staphylococcus Aureus in the Oral Cavity

الباحثونEnass A.K. Almkhadhree، Kawther Alqaseer 2 , Ohood Aqeed Radhi 3 , Baleegh A Kadhim 4 , Mansour Abdullah Falah 5 , Hawraa G. I. Al-Yasseree 6 , Wijdan Dhaidan Shnain 7 , Intisar Jameel Albandar 8 , Esraa Shaker
المجلةKufa Journal for Nursing Sciences
مختصر البحث

The oral cavity is habitat to a wide variety of commensal flora, which may act as a reservoir of factors that influence drug resistance. Bacteria in the oral cavity create biofilms, which makes it easier for horizontal gene transfer to result in the accumulation of antibiotic resistance genes. Methicillin-resistant Staphylococcus aureus (MRSA) carriage rates in the oral cavity are high, according to recent studies. The widespread use of antibiotic prophylaxis among at-risk dental procedure applicants may facilitate MRSA establishment in the mouth. These modifications in the epidemiology of MRSA have significant ramifications for clinical practice, methodological approaches to MRSA carriage studies, and MRSA prevention efforts.

2023

Community-Associated Methicillin-Resistant Staphylococcus Aureus in the Oral Cavity

الباحثونEnass A.K. Almkhadhree، Kawther Alqaseer 2 , Ohood Aqeed Radhi 3 , Baleegh A Kadhim 4 , Mansour Abdullah Falah 5 , Hawraa G. I. Al-Yasseree 6 , Wijdan Dhaidan Shnain 7 , Intisar Jameel Albandar 8 , Esraa Shaker
المجلةKufa Journal for Nursing Sciences
مختصر البحث

The oral cavity is habitat to a wide variety of commensal flora, which may act as a reservoir of factors that influence drug resistance. Bacteria in the oral cavity create biofilms, which makes it easier for horizontal gene transfer to result in the accumulation of antibiotic resistance genes. Methicillin-resistant Staphylococcus aureus (MRSA) carriage rates in the oral cavity are high, according to recent studies. The widespread use of antibiotic prophylaxis among at-risk dental procedure applicants may facilitate MRSA establishment in the mouth. These modifications in the epidemiology of MRSA have significant ramifications for clinical practice, methodological approaches to MRSA carriage studies, and MRSA prevention efforts.

2023

Community-Associated Methicillin-Resistant Staphylococcus Aureus in the Oral Cavity

الباحثونEnass A.K. Almkhadhree، Kawther Alqaseer 2 , Ohood Aqeed Radhi 3 , Baleegh A Kadhim 4 , Mansour Abdullah Falah 5 , Hawraa G. I. Al-Yasseree 6 , Wijdan Dhaidan Shnain 7 , Intisar Jameel Albandar 8 , Esraa Shaker
المجلةUniversity of Kufa, Faculty of Nursing
مختصر البحث

The oral cavity is habitat to a wide variety of commensal flora, which may act as a reservoir of factors that influence drug resistance. Bacteria in the oral cavity create biofilms, which makes it easier for horizontal gene transfer to result in the accumulation of antibiotic resistance genes. Methicillin-resistant Staphylococcus aureus (MRSA) carriage rates in the oral cavity are high, according to recent studies. The widespread use of antibiotic prophylaxis among at-risk dental procedure applicants may facilitate MRSA establishment in the mouth. These modifications in the epidemiology of MRSA have significant ramifications for clinical practice, methodological approaches to MRSA carriage studies, and MRSA prevention efforts.

2023

USES BACILLUS SUBTILIS, RHIZOBIUM BACTERIA, AND ARBUSCULAR MYCORRHIZAL FUNGI TO ENHANCE SOME PHYSICAL AND CHEMICAL CHARACTERISTICS GROWTH ON APRICOT SAPLING (PRUNUS ARMENIACA L)

الباحثونOhood Aqeed Radhi، Hawraa Ghaleb Idreess Kawther Alqaseer and Ali.S. A. Aljanabi
المجلةANNALS OF FOREST RESEARCH
مختصر البحث

The current study assesses the effects of utilizing Bacillus subtilis, Rhizobium bacteria, and Arbuscular mycorrhizal fungus as a biofertilizer on apricot sapling cultivar Bayaa. Concurrently, the use of to promote plant growth was developed. Furthermore, three factors were used. The first component was added for soil apricot sapling by dilution suspension of Bacillus subtilis with three levels (0, 100, 200 ml.L-1) while the second factor was added by dilution suspension of Rhizobium spp. with two levels (0, 200 ml.L-1) and third factor was dilution suspension add Arbuscular mycorrhizal fungus with three levels (0, 10, 20 ml.L-1). The results demonstrate that adding Bacillus subtilis bacteria to the soil of apricot saplings at both levels (100, 200 ml.L-1) had a significant influence on the leaf area, total chlorophyll, N%,P%,Mg%, and reduced proline and peroxidase. The effects of Rhizobium bacteria at level (200 ml.L-1) on all trails under study were comparable to non-addition of Bacillus subtilis .Arbuscular mycorrhizal fungus of the treated saplings at both levels (10 and 20 ml.L-1) to the soil of apricot saplings had a significant effects on the leaf area, the increase in the heigh,total chlorophyll ,N%,P%,Mg% and reduce proline and peroxidase. The interaction among Bacillus subtilis, Rhizobium bacteria, and Arbuscular mycorrhizal fungi were effects on trails under study especially (20 ml.L-1Arbuscular mycorrhizal +200 ml.L-1 Rhizobium + 200 ml.L-1 Bacillus subtilis) treatment, it was high significant in all trails.

2022

Nosocomial Infections Associated with Caesarean Section

الباحثونOhood Radhi، Alaq Hameed Ali Kawther Alqaseer
المجلةKufa Journal for Nursing Sciences (KJNS)
مختصر البحث

Nosocomial infections, also called health-care-associated or hospital-acquired infections, are a subset of infectious diseases acquired in a health-care facility. Historically, Staphylococci, Pseudomonas, and Escherichia coli have been the common known as nosocomial infection bacteria. Moreover, nosocomial pneumonia, surgical wound infections, and vascular access-related bacteremia have caused the most illness and death in hospitalized patients; and intensive care units have been the epicenters of antibiotic resistance . Acquired antimicrobial resistance is the major problem, and vancomycin-resistant Staphylococcus aureus is the pathogen of greatest concern. The shift to outpatient care is leaving the most vulnerable patients in hospitals. Aging of our population and increasingly aggressive medical and surgical interventions, including implanted foreign bodies, organ transplantations, and xenotransplantation, create a cohort of particularly susceptible persons. Moreover, renovation of aging hospitals increases risk of airborne fungal and other infections . To prevent and control these emerging nosocomial infections, we need to increase national surveillance, "risk adjust" infection rates so that inter hospital comparisons are valid, develop more noninvasive infection-resistant devices, and work with health-care workers on better implementation of existing control measures such as hand washing . In this review we aimed to review the previous projects which study incidence of hospital infection among delivery women with caesarean section in hospitals. Also, to discuss about the nosocomial infections and its types. We will also review the most common way a nosocomial infection is acquired, and the most common cause of nosocomial infection. In order to the modes of transmission of infection. In addition to a way to prevent nosocomial infections in hospitals.

2022

Preventive Measures Pursued by College Students for The Prevention of Coronavirus in University of Kufa

الباحثونMansour A. Falah، Kawther Alqaseer
المجلةKufa Journal for Nursing Sciences (KJNS)
مختصر البحث

Background: Coronavirus disease 2019 (COVID-19) is the latest pandemic with a high rate of morbidity and mortality worldwide. Crises like these can harm the academic functioning and psychophysical health of students. Students have an important role in controlling the spread of infectious diseases by pursuing prophylactic measures and this quantitative study. Objectives: the study aims to explore how students perceive the COVID-19 crisis and what their personal experiences were while studying during the global pandemic. Methodology: It is a descriptive study on Preventive measures pursued by college students for the prevention of Coronavirus, where the sample was collected from twenty-five universities, were collected (427) among students who are studying in a different field, and the majority of them was studied at the University of Kufa (53%), the samples were collected by a questionnaire prepared and designed in two parts, the first part consists of demographic information (7 items) and the second part Preventive measurement pursued by college students (18th item). Results: The study showed that the means of scores of satisfaction of the preventive measurement (high), and also there is a no relationship between the demographic information and preventive measures, the overall total assessment is also high. Recommendations: Overall, the researcher was able to prove that college students have sufficient knowledge and awareness of COVID-19, and the majority are willing to apply safety measures in the prevention of the coronavirus Continued access to online health information resources like free courses, clinical management guidelines, and webinars on COVID-19 offered internationally.

2021

Balance between Protection and Pathogenic Response to Aerosol Challenge with Mycobacterium tuberculosis (Mtb) in Mice Vaccinated with TriFu64, a Fusion Consisting of Three Mtb Antigens

الباحثونSadaf Sulman ، Benjamin O. Savidge , Kawther Alqaseer , Mrinal K. Das , Neda Nezam Abadi , John E. Pearl , Obolbek Turapov , Galina V. Mukamolova , M. Waheed Akhtar 2 and Andrea May Cooper
المجلةUniversity of Leicester
مختصر البحث

Abstract: Tuberculosis vaccines capable of reducing disease worldwide have proven difficult to develop. BCG is effective in limiting childhood disease, but adult TB is still a major public health issue. Development of new vaccines requires identification of antigens that are both spatially and temporally available throughout infection, and immune responses to which reduce bacterial burden without increasing pathologic outcomes. Subunit vaccines containing antigen require adjuvants to driveappropriatelong-livedresponses. Wegeneratedatriple-antigenfusioncontainingthevirulenceassociated EsxN (Rv1793), the PPE42 (Rv2608), and the latency associated Rv2628 to investigate the balance between bacterial reduction and weight loss in an animal model of aerosol infection. We found that in both a low pattern recognition receptor (PRR) engaging adjuvant and a high PRRengaging adjuvant (MPL/TDM/DDA) the triple-antigen fusion could reduce the bacterial burden, but also induced weight loss in the mice upon aerosol infection. The weight loss was associated with an imbalance between TNFα and IL-17 transcription in the lung upon challenge. These data indicate the need to assess both protective and pathogenic responses when investigating subunit vaccine activity.

2021

Saussurea lappa: An Important Medicinal Plant for Treatment Different Diseases: A review

الباحثونAlaq hameed ali، Dr. Kawther Alqaseer Duaa Fatlawi Salma Shehab Dr. Mansour Falah Dr. Mohammed Hassan Dr. Wijdan Shnain Dr. Ohoud Radhi
المجلةUniversity of Kufa
مختصر البحث

Saussurea lappa is belong to the family Astreaceae. It has been cultivated in various parts of the world a commonly known and potent plant which is well studied for its medicinal uses in diverse indigenous Indian systems of medicine. .

2019

Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112

الباحثونKawther Alqaseer، Obolbek Turapov Philippe Barthe Heena Jagatia Angélique De Visch Christian Roumestand Malgorzata Wegrzyn Iona L. Bartek Martin I. Voskuil Helen M. O'Hare Paul Ajuh Andrew R. Bottrill Adam A. Witney Martin Cohen‐Gonsaud Simon J. Waddell Galina V. Mukamolova
المجلةUniversity of Leicester
مختصر البحث

Mycobacterium tuberculosis (Mtb) is able to persist in the body through months of multi‐drug therapy. Mycobacteria possess a wide range of regulatory proteins, including the protein kinase B (PknB) which controls peptidoglycan biosynthesis during growth. Here, we observed that depletion of PknB resulted in specific transcriptional changes that are likely caused by reduced phosphorylation of the H‐NS‐like regulator Lsr2 at threonine 112. The activity of PknB towards this phosphosite was confirmed with purified proteins, and this site was required for adaptation of Mtb to hypoxic conditions, and growth on solid media. Like H‐NS, Lsr2 binds DNA in sequence‐dependent and non‐specific modes. PknB phosphorylation of Lsr2 reduced DNA binding, measured by fluorescence anisotropy and electrophoretic mobility shift assays, and our NMR structure of phosphomimetic T112D Lsr2 suggests that this may be due to increased dynamics of the DNA‐binding domain. Conversely, the phosphoablative T112A Lsr2 had increased binding to certain DNA sites in ChIP‐sequencing, and Mtb containing this variant showed transcriptional changes that correspond with the change in DNA binding. In summary, PknB controls Mtb growth and adaptations to the changing host environment by phosphorylating the global transcriptional regulator Lsr2.

المحاضرات

16

General Safety and Microscope

Practical Microbiology

Sterilisation and Disinfection

Practical Microbiology

Cultivation of Bacteria

Practical Microbiology

Gram stain

Practical Microbiology

Lecture one

English

Lecture Two

English

Virology

Microbiology

Mycology

Microbiology

Mycobacteria

Microbiology

Type of Nursing

English

Hospital teams

English

Nutrition

English

Hospital departments

English

Avoid repetition

English

Modal verbs

English

prepositions

English

الأخبار والإعلانات

15
الأخبار 2023-08-07

لجنة جامعية لمتابعة سير الامتحانات في الكليات الحكومية

لجنة جامعية لتفقد سير الامتحانات النهاية للكورس الثاني للاطلاع على واقع الامتحانات والاطلاع على استعدادات الكليات من اجل توفير افضل الاجواء للطلبة

الأخبار 2023-08-07

لجنة وزارية لتفقد سير الامتحانات في الكليات الاهلية

عضو لجنة وزارية لتفقد سير الامتحانات في الكليات الاهلية ومراقبة سير الامتحان

الأخبار 2023-08-07

اجتماع مع مسؤولي المختبرات في الجامعة

تم عقد اجتماع مع مسؤولي وحدة المختبرات في الجامعة لغرض اطلاعم على توجيات الوزارة بخضوص النهوض بواقع المختبرت التعليمية

الأخبار 2023-08-07

ورشة عمل في وزارة التعليم العالي

تم حضور ورشة العمل التي تم عقدها في جامعة بغداد من قبل جهاز الاشراف والتقويم الجامعي بخصوص المعايير العراقية لجودة المختبرات التعليمية

الأخبار 2023-08-07

حلقة نقاشية

تم عقد حلقة نقاشية مع مسؤولي المختبرات في كلية التمريض

الأخبار 2023-08-07

سمنار

تم القاء سمنار عن البحث المخطط لهذه السنة الدراسية

الأخبار 2023-08-07

حلقة نقاشية

تم عقد حلقة نقاشية على كيفية ملئ استمارة التحقق للمعايير العراقية لجودة المختبرات التعليمية

الأخبار 2023-08-07

دورة تدريبية حول الامراض الانتقالية

الأخبار 2023-04-18

مهرجان ثقافي

اقام فرع العلوم الاساسية مع شعبة النشاطات الطلابية مهرجان ثقافي بمناسبة اليوم العالمي للغة العربية بتاريخ 18-12-2022

الأخبار 2023-04-18

اكتوبر الوردي

اقامت كلية التمريض بالتعاون مع دائرة صحة النجف- قسم الصحة العامة وحدة النوع الاجتماعي حملة تثقيفية توعوية تطوعية بعنوان اكتوبر الوردي للتوعيه حول الكشف المبكر عن سرطان الثدي

الأخبار 2023-04-12

ورشة عمل حول السلامة في المختبرات

تم عقد ورشة عمل لكل مسؤولي المختبرات في كلية التمريض لغرض توعيه الطلبة بالاحتياطات الواجب اتخاذها قبل دخولهم المختبرات

الأخبار 2022-11-05

ورشة عمل

الأخبار 2022-03-23

حلقة نقاشية بعنوان مقاومة الانسولين

حلقة نقاشية بعنوان ( مقاومة الأنسولين ) والتي حضرها تدريسيين وموظفين كليتنا وهي حالة فيزينولوجية يصبح فيها الانسولين اول فعالية في تخفيض مستوى السكر في الدم يمكن لها ان ترتفع الى عدة مستويات تصل الى خارج نطاق المستوى العادي وتسبب اثار صحية ضارة

الأخبار 2022-03-23

حلقة نقاشية عن المواد الحافظه واضرارها على الصحة

الأخبار 2022-03-23

ورشة عمل حول معايير المختبر الجيد والمشاكل التي تواجه المختبرات

ورشة عمل بعنوان (معايير المختبر الجيد والمشاكل التي تواجه المختبرات) لسؤولي اعتماد المختبرات في كليات الجامعة ، تضمنت الورشة محاضرة القتها مديرة قسم الجودة الدكتورة الاء الناهي حول معايير المختبر الجيد ومحاضرة اخرى للدكتورة كوثر عدنان عن المشاكل التي تواجه مختبرات الكليات وتطرق المحاضرون لآلية العمل في المختبرات وكيفية كتابة الطرائق الإجرائية المطابقة لمواصفات الجودة ، وخلصت الورشة الى ضرورة اخضاع المختبر إلى منظومة حماية متكاملة والاهتمام بالطرائق الاجرائية المتمثلة بضبط الوثائق والسجلات وبيئة العمل والإجراءات التصحيحية والوقائية للمختبر .

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