وجدان راجح حمزه الكريطي

The present study was aimed efficiency to evaluate the unsaturated fatty acid omega-3 in reducing the side effects that resulted from administration of cyclosporine drug in white New Zealand rabbits.(60) from white males' rabbits were used in this study, the animals divided into major four groups (15) rabbits per group and its subdivision into three groups (5) rabbits per group. The first group is orally administered with normal saline, second groups were administered cyclosporine (25mg/kg) only. Third groups were administered cyclosporine (25mg/kg) in the first day and Omega-3 (500mg/kg) in the second day, while Fourth groups were administered cyclosporine (25mg/kg) in the first day and omega-3 (1000mg/kg) in the second day for periods (21, 30, 60) days respectively. After ending study periods, the animals were sacrificed and the blood was collected and samples from liver were taken and the results were showed the following: the histological study showed pathological changes after administration of cyclosporine (25mg/kg) with blood congestion for period (21day), while severe blood congestion with beginning of fibrosis for period (30day) while in the period (60day) very severe blood congestion with aggregation of inflammatory cells and grow of fibroblast cells were showed. while the interaction between cyclosporine and two concentrations (500&1000mg/kg) of omega-3 were showed non-pathological changes in liver tissues. From this study concluded that omega-3 have an important role in the reducing histopathology side effects that result from administration of cyclosporine drug in white rabbits.

In the current study, Seventy menopausal women have CHD were admitted to the coronary care unit of AL-Sader teaching hospital in AL-najaf AL-Ashraf during the period from January to April/2016 for the ages were ranging from 40 to 69 years old. The samples were divided into three groups (SA 25, UA 22, AMI 23), while the healthy group was composed of 20. The current study indicated a significant decrease (P<0.05)in serum E2 and GS concentration of CHD compared with healthy group. The serum of E2 and GS concentrations showed a significantly decrease (p<0.05) in AMI compare with UA and SA groups of CHD. The result indicated a positive correlation between E2 and GS

The study is intended to asses serum levels of Thrombospondin-1, fasting blood glucose in type 2 diabetic patients, also correlation between Thrombospondin-1 in both males and females. The study was conducted on randomly selected 65 type 2 diabetic patients (34 males and 31 females) attending the diabetes mellitus center in Al-Sadder Teaching City in Al-Najaf province, Iraqi and a group of 24 apparently healthy subjects (12 Males and 12 Females) were included as a control group. The Study was carried out from August 2013 to February 2014. The patients' age was ranging from 35 to 64 years old. The results indicated a significant increase (p<0.05) in serum FBG and TSP-1 levels in diabetic patients in comparing with healthy groups. The results also revealed no significant differences (p>0.05) in serum TSP-1 levels between males and females in both patients and healthy groups, while the results of FBG …