دكتورة وداد ابراهيم يحيى الخزاعي

A new series of mixed ligand complexes synthesized and characterized using of azo ligand derived from (5-methyl— imidazole) with (8-hydroxy quinolone). New mix-ligand structures and their transitional metal complexes were fully characterized using several techniques, including molar conductance, elemental analysis (C.H.N), electronic spectral, magnetic measurements, 1HNMR, spectral studies, and mass spectra. The data shows that these complexes have a composition of [ML(8-HQ) Cl2] H2O where M = Co(II), Zn(II), Cu(II), X=0, and Ni(II), X=1, [ML(8-HQ)] Cl. where M=Pd. The electronic spectral data and magnetic susceptibility calculations of the complexes indicate that the octahedral geometry of all complexes, except for the Pd(II) complex, indicates a planar-square geometry. The results demonstrate that the nitrogen of the imidazole ring and azo nitrogen atom of the primary ligand are coordination sites with a nitrogen atom and oxygen atom of a secondary ligand of the (8-HQ) in the basic medium. Biological effects of the palladium (II) complex are screening against human breast cancer (MCF-7 and AMJ-13) and normal cells (HBL) were examined, which indicated colon cancer cell line LS-174. The results show the highest activity effect for the complex

A photocatalyst aluminum oxide Al2O3 Nanoparticles was effectively prepared by electrochemical method using electrolysis cell which contains stainless steel (1cm 2) and aluminium plate (1cm2) were worked as a cathode and anode electrodes respectively. The synthesized Al2O3 Nanoparticles sample was identified by Fourier transform infrared (FTIR), X-ray diffraction (XRD), and Field Emission Scanning Electron Microscope (FE-SEM) with (EDS) analysis. The XRD pattern specified that prepared Al2O3 sample had a crystal structure for γ-Al2O3with average crystal size (3nm) was achieved at (1000°C) calcination temperature. FTIR spectra indicated the existence of O–Al–O bonds vibration and hydroxyl group in the sample. The FESEM images gave morpholgy of Al2O3 nanoparticles powder after calcination to 1000°C was spherical shape and the particles were attached to each other, leading to an increase in particle size. The EDS measurements indicated the presence of Al with O peaks. The experimental results of the Al2O3 photocatalyst calcined at 1000°C for two hours showed photocatalytic efficiency to degradation Chromotrope -E122 dye under UV light.

A new series of transition metal complexes of Mn(II), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II), Hg(II), and Au(III) were synthesized from Azo ligand (HL) derived from 1,3- dihydroxynaphthalene with 4-amino acetophenone. The structural features were derived from their elemental analysis, Mass, 1H-NMR, C13NMR in addition to elemental analysis measurement. All complexes were identification by elemental analysis, magnetic susceptibility. Molar conductance of the transition metal complexes was determined in (DMSO) using Digital Conductivity Series Ino Lab- 720 at 25 °C with IR and UV-Vis spectral studies. The results indicating the octahedral geometry for all compounds of l:2 M:L chelates type formula while the complexes which have general formula but l:l M:L cheats type with Au(III)ion except which has square planer geometry . (L1) ligand behaved as bidentate through nitrogen atom of azo group and oxygen atom of hydroxyl group in the basic medium, all complexes that non-electrolytes and no conductive species accepted Au (III)-complex is electrolyte nature. Antimicrobial screening tests were performed against fungi sensitive organisms as Candida albicans, as antifungal. The DNA cleavage activities of azo dyes and their complexes have been studied by the agarose gel electrophoresis method. The activity data show that the metal complexes higher antifungal activity than the free ligand. The result is discussed. RESUMEN. Una nueva serie de complejos de metales de transición de Mn (II), Fe (II), Co (II), Ni (II), Cu (II), Zn (II), Cd (II), Hg (II) y Au (III) se sintetizaron a partir de ligando azo (HL) derivado de 1,3-dihidroxinaftaleno con 4-amino acetofenona. Las características estructurales se derivaron de su análisis elemental, Masa, 1HNMR, C13NMR además de la medición del análisis elemental. Todos los complejos fueron identificación por análisis elemental, susceptibilidad magnética. La conductancia molar de los complejos de metales de transición se determinó en (DMSO) usando la serie de conductividad digital Ino Lab-720 a 25 °C con estudios espectrales IR y UV-Vis. Los resultados indican la geometría octaédrica para todos los compuestos de fórmula de tipo 1:2 M:L quelatos, mientras que los complejos que tienen fórmula general pero 1:1 M:L tipo trampa con ion Au (III) excepto los que tienen geometría de cepillado cuadrado. El ligando (L1) se comportó como bidentado a través del átomo de nitrógeno del grupo azo y el átomo de oxígeno del grupo hidroxilo en el medio básico, todos los complejos que no son electrolitos y especies conductoras aceptaron Au (III)-complejo es de naturaleza electrolítica. Se realizaron pruebas de detección de antimicrobianos como antifúngicos en organismos sensibles como Candida albicans. Las actividades de escisión del ADN de los colorantes azoicos y sus complejos se han estudiado mediante el método de electroforesis en gel de agarosa. Los datos de actividad muestran que los complejos metálicos tienen una mayor actividad antifúngica que el ligando libre. Se discute el resultado.

Azo compounds contain two aromatic rings separated by an azo (-N=N-) link. These are versatile molecules that have garnered a lot of interest in both basic and applied research. In this work, synthesis of some Azo dyes derivatives by coupling P-cresol with diazonium salts obtained from p-chloroaniline and p-methoxyaniline. The structure of the synthesized compound has been characterized by using techniques like UV-Vis Spectroscopy, and Fourier-transform infrared spectroscopy (FTIR). In addition, the antimicrobial activity of these synthesized dyes compounds was examined by using the disc diffusion method against gram negative and gram positive bacteria Staphylococcus aureus and Pseudomonas aeruginosa which have been isolated from the patients of wound infection. Further, synthesized compounds showed moderate to significant inhibitory effect at the selected concentrations against the tested microorganisms. The results of antibacterial activities demonstrated that compound p-chloroaniline had good antibacterial activity against S. aureus and P. aeruginosa at the concentration of 300 mg/ml with 8.079 mm and 6.16 mm inhibition zone, diameter respectively. This study synthesized two new compounds viz., p-chloroaniline and p-methoxyaniline, and among these two p-chloroaniline has good anti-bacterial activity against S. aureus. Therefore, this can serve as a new compound for the manufacture of ointment to treat wound infections.

A new azo compounds is prepared by coupling the diazonium salts of (2- Cyano aniline) with 1,3- dihydroxynaphthalene to form (E)-2-((2,4-dihydroxynaphthalen-1- yl) diazenyl)benzonitrile. The azo ligand was identified by : Mass, 1H-NMR, C13NMR,UV-Vis. and IR spectra, in addition to elemental analysis measurement. The chelate complexes were characterized by elemental analysis , magnetic susceptibility, Molar conductance , UV-Vis. and IR spectra . The geometry of metal complexes were proposed based on analytical and spectral data . Analytical data revealed that all the complexes exhibited 1:2 metal–ligand ratio. On the basis of magnetic susceptibility measurements, suitable geometry was proposed for each complex. IR spectra of complexes show that the ligand is coordinated to the metal ions in bidentate manner with Oxygen and Nitrogen donor sites of hydroxynaphthalene (OH) and azo Nitrogen, which suggest octahedral geometry for all complexes. Also, biological evaluation of all synthesized compound shows moderate to good activity against Candida

Azo compounds are the oldest and largest class of industrially synthesized organic dyes due to their versatile application in various fields and have attracted much attention in both academic and applied researches. The latter included dyeing textile fiber, biomedical studies, advance application in organic synthesis and high technology areas such as laser, liquid crystalline displays, electro-optical devices and ink-jet printers. Therefore, current study was conducted to synthesize new azo-dyes and to study their chemical structures in details. Methods: A new azo compounds is prepared by coupling the diazonium salts of (3-amino pyridine) with 1,3- dihydroxynaphthalene to form (E)-4-(pyridin-3-yldiazenyl) naphthalene-1,3-diol. The azo ligand was identified by: Mass, 1H-NMR, C13NMR,UV-Vis. and IR spectra, in addition to elemental analysis measurement. The chelate complexes were characterized by elemental analysis, magnetic susceptibility, molar conductance, UV-Vis and IR spectra. Results: Analytical data revealed that all the complexes exhibited 1:2 metal–ligand ratios. On the basis of magnetic susceptibility measurements, suitable geometry was proposed for each complex. IR spectra of complexes showed that the ligand is coordinated to the metal ions in bidentate manner with Oxygen and Nitrogen donor sites of hydroxynaphthalene (OH) and azo Nitrogen. These findings suggested octahedral geometry for all complexes. Also, biological evaluation of all synthesized compound showed moderate to good activity against employed strains. All the complexes were stable, non-ionic and exhibited octahedral geometry around the metal center.

مناقشة طالب الماجستير احمد علي حسين في كلية العلوم جامعة الكوفة