2019
Human Papilloma Virus Expression in Sample of Iraqi Patients with Premalignant and Malignant Laryngeal Lesions (Immunohistochemical Study (
AuthorsRanda Saad Hameed Al-Battawi , Lecturer Dr. MAIS M SALIM MOHAMMEDHASAN ALMURTADHA, Lecturer Dr. Iftikhar Khdhair Abbas, Prof. Dr. Liwaa Hussein Mahdi Al-Kilabi
JournalKUFA JOURNAL FOR NURSING SCIENCES
Abstract
Background: Human Papilloma Virus is a DNA virus, epitheliotropic, non-enveloped, with a double strand circular genome, and about 8,000 pb, measuring 55 nm in diameter. Material and Method: Fifty cases of laryngeal cancer and premalignant laryngeal lesions are incorporated within this study. Tissue was saved with formaldehyde and embedded in paraffin blocks. We used Immunohistochemical technique in order to prove the correlation between HPV infection and those laryngeal lesions. Results: We obtained about (47,5 %) HPV positive in laryngeal squamous cell carcinoma and about (20%) HPV positive in premalignant laryngeal lesions.