Naser Abdulhasan Naser Almatwari

A highly reliable approach for assessment of copper(II) in blood serum samples using an organic molecule 4-(3-hydroxyphenylazo)resorcinol, 4-HAR was developed. The paper presents the synthesis of 4-HAR, which serves as probe for definite species. 4-HAR was characterized with the FT-IR, UV-visible, 1H-NMR, 13C-NMR and mass analysis, thermal TG and DSC techniques. After examining its interactions with more than twenty five metal ions, it was found that 4-HAR showed reaction only with copper(II), giving a distinct green color at λmax 603 nm. Experimental conditions for the reaction of 4-HAR with copper(II) were optimized. A calibration curve was created and the exhibition range of concentration obeyed Beer's Law from 0.30 to 16 μg.mL-1 with correlation coefficient of r = 0.9986, and value of the molar absorption coefficient, ε, being 3314 L.mol- 1.cm-1. The analytical method was used to determine copper(II) levels in several blood serum samples. The amounts of copper(II) found in the sera samples were compared with flame atomic absorption spectrometry technique, and the results were found to be highly reliable. Based on validation, the new approach can be utilized for assurance quality purposes with a high degree of confidence.

A modern development discusses the synthesis and validity of simple, sensitive, and versatile spectrophotometric methods for Bi(III) and Al(III) determination in pharmaceutical formulations have been conducted. In the present paper, 4-(4 acetamidophenylazo) pyrogallol has been synthesized as a new organic compound, 4-APAP, by coupling pyrogallol in a regulated pH medium with diazotized p-aminoacetanilide. 4-APAP was identified by methods of FT-IR, 1H-NMR, 13C-NMR, and thermal analysis (thermogravimetry and differential scanning calorimetry). Solvatochromic activity was also studied in solvents with different polarities. The Kamlet and Taft linear solvation energy relationship was used to correlate shifts in UV-Visible spectra of 4-APAP with Kamlet-Taft parameters (α, β, and π*). The optimum assay conditions showed linearity from 0.3-13 to 0.5-11 μg‧mL-1 for Bi(III) and Al(III), respectively. Molar absorptivity values were 3.365 × 104 and 0.356 × 104 L‧mol-1‧cm-1 for Bi(III) and Al(III), with similar Sandell’s sensitivity measures of 0.006 and 0.008 μg‧cm-2. Detection limits and quantification limits were 0.013 and 0.043 μg‧mL-1 for Bi(III), respectively, and 0.018 and 0.059 μg‧mL-1 for Al(III) with the relative standard deviation for determination of both metal ions using 4-APAP probe being <2.0%. The validity, accuracy, and efficiency of the approaches were demonstrated by the determination of Bi(III) and Al(III) in different formulations.

A new approach describing the validation and development of an easy, new spectrophotometric and kinetic method for identification of para-aminobenzoic acid in dietary supplement has been performed. In this study, para-aminobenzoic acid was derived in a pH-controlled environment, as a new organic compound 4(4-Benzophenylazo)pyrogallol, by incorporating diazotized para-aminobenzoic acid with pyrogallol.

A new trend describes the development and validation of a simple, sensitive and selective kinetic spectrophotometric methods for the determination of sulfadiazine in pharmaceutical formulations has been conducted. In this paper, sulfadiazine was derivatized as a new organic compound 4(4-sulphophenylazo) pyrogallol, 4-SPAP, by coupling pyrogallol with diazotized sulfadiazine in medium of controlled pH. 4-SPAP was characterized by techniques of FT-IR, H-NMR, GC-Mass, TG and DSC thermal analysis methods. Solvatochromic behavior in solvents of various polarities was also investigated.

A new, simple, sensitive and rapid spectrophotometric method is proposed for the determination of cholesterol. The method is based on the diazotization reaction of procaine hydrochloride with sodium nitrite in hydrochloric acid medium to form diazonium salt, which is coupled with cholesterol in alkaline medium to form soluble products. The reaction product with cholesterol was azoxy which showed maximum absorption at 428nm. After optimization, the calibration curves were constructed, and subsequently. Result was found that Beer's law obeyed within concentration ranges of 1–15 μg.mL-1of cholesterol. The molar absorptivity was 1.824×104 L.mol-1.cm-1, Sandellʼs sensitivity was0.0213 μg.cm-2, R.S.D% was 0.578% , with a correlation coefficient of 0.9798 for cholesterol . The interferences were studied, they didn't effect on concentration determination of cholesterol. The method was successfully applied for determination of cholesterol in serum blood and milk. Keywords: cholesterol, spectrophotometry, milk, serum blood.

A rapid,simple, and sensitive spectrophotometric approach for theassessment of microgram amounts of chlorpromazine hydrochloride drug in aqueous solution is described. The method is based on the oxidative coupling reaction between chlorpromazinehydrochloride and N-methyl-p-hydroxy aniline (metol)in thepresence of sodium periodate andhydrochloride acid to form an intense redcolored product withmaximum absorption at 526 nm. Beer’s law is obeyed over the concentrationrange of(1-20)μg.ml-1 with molar absorptivity of 1.597x104l.mol-1.cm-1 and Sandell`s sensitivity of 0.022μg.cm-2. The approach does not resort totemperature control or to solvent extraction. Theoptimum conditions for all color development are described and the proposedmethod has been successfully applied for the assessment of chlorpromazinehydrochloride in bulk drug and pharmaceutical preparations(Largactil drug). The commonexcipients and additives did not interfere in this approach .

BCS covers the latest developments in various fields of biomedicine such as cardiology, immunology, genetics, environmental health, neurology, oncology and toxicology. Allied disciplines such as biochemistry and biophysics will also be considered for publication.

After reviewing seventeen research articles for Talanta, I was awarded the Outstanding Reviewer Certificate

I was selected as editorial board in Journal of Education, Teaching and Social Studies

I was chosen as the ambassador of this publishing house, which has more than 100 magazines in various scientific, medical and engineering disciplines, natural sciences and several specializations. 38 magazines registered with the 2018 Journal of Citation Reports. On this occasion, I am pleased to invite brothers and sisters researchers from our university to strive for publication in the magazines of this publishing house, which will return with the good scientific reputation of the researcher and the university. More information can be found at http://benthamscience.com/