2024
A study of the prevalence of PGR gene expression with ER and PR Receptor markers positivity in female breast cancer cases in Al-Najaf province, Iraq
الباحثونJinan H. Alfatlawi ، Mohammad J. Alzeyadi; Ali H. Abood
المجلةEgyptian Journal of Medical microbiology
التاريخ2024-09-04
مختصر البحث
Breast cancer is the leading cause of mortality among women globally. Numerous predisposing risk factors have been identified, making their incidence constantly increasing. Progesterone and the receptors for it binds to have critical roles in mammary gland development and breast carcinogenesis, indicating. Progesterone and its associated signaling pathways are necessary factors in initiating, advancing, and maintaining the neoplastic phenotype of the mammary gland. PR status is an important biomarker for classifying breast cancer subtypes and predicting prognosis.