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د. اسراء عبد الجبار جلوب الجنابي
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د. اسراء عبد الجبار جلوب الجنابي

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د. اسراء عبد الجبار الجنابي ماجستير علوم الاحياء المجهرية الطبية medical microbiology - و دكتوراة في المناعة والاحياء الجزيئي كلية العلوم تخصص دقيق في mucosal immunity -المواد التي ادرسها في قسم العلوم المختبرية والسريرية 1-البكتريا 2- المناعة 3- الطفيليات -الاشراف على بحوث التخرج - الاهتمامات البحثية 1- الاستجابة المناعية للامراض البكتيرية وامراض المناعة الذاتية 2- الاستجابة المناعية للامراض السرطانية 3- اللقاحات البكتيرية 4- العلاج المناعي
البحوث المنشورة

1 عزل وتشخيص البكتريا الممرضة الهوائية المسببة لالتهاب ملتحمة العين conjunctivitis في مستشفى الفرات الاوسط في الكوفة - مجلة القادسية لعلوم الطب البيطري
2- دراسة قابلية بكتريا Pseudomonas fluorescens على التضاد مع بعض انواع البكتريا المرضية وبيان مدى حساسيتها تجاة بعض المضادات الحياتية مجلة القادسية للعلوم الطبية
3 دراسة ميكروبايلوجية مقارنة للبكتريا المرضية الهوائية المسببة لالتهاب المجاري البولية بين المرضى الراقدين وغير الراقدين في مستشفى النجف العام مجلة جامعة بابل
4-- SYNOVIAL MUCOSAL CYTOKINES AND CHAPEROKINE IN Staphylococcus aureus HUMAN SEPTIC A RTHRITIS World Journal of Pharmaceutical Research
:5- انتشار جينات sea,hla,and spa بين عزلات بكتريا Staphylococcus aureusالمقاومة للميثيسيلين والمتعلقة باالتهاب المفاصل االبكتيري World Journal of Pharmaceutical Researc
6-Antimicrobial sensitivity pattern of pathogenic bacteria isolated from olderwomen with asymptomatic bacteriuria.Biomedical Research 2018; 29 (12): 2597-2601
7-RESEARCH ARTICLE
Prevalence of aerobic pathogenic bacteria isolated from patients
with burn infection and their antimicrobial susceptibility patterns
in Al-Najaf City, Iraq- a three-year cross-sectional study.F1000Research 2018, 7:1157 Last updated: 31 JUL 2018
8-Profile of Antimicrobial Resistance of Aerobic Pathogenic Bacteria isolated
from Different Clinical Infections in Al-Kufa Central Hospital –Iraq
During period from 2015 to 2017 .Research J. Pharm. and Tech. 10(10): October 2017
9-Prevalence of some virulence associated-genes in
methicillin resistance Staphylococcus aureus
isolates from patients infected with septic arthritis
and antimicrobial resistance patterns of these
isolates.BIOSCIENCE RESEARCH, 2018 15(3):2441-2451
,

الاهتمامات البحثية

9

البحوث المنشورة

15
2022

Prevalence of pulmonary tuberculosis in Al-Najaf governate, Iraq

الباحثونSaleem Khteer Al-Hadraawy، Kais Khudhair Alhadrawi2, Israa Abduljabbar Jaloob Aljanaby3, Ahmed Abduljabbar Jaloob Aljanaby 1, Rahman S Zabibah
المجلةF1000Research
مختصر البحث

Abstract Background: pulmonary tuberculosis (PTB) is one of the most global dangerous infectious diseases worldwide, particularly in developing countries. Mycobacterium tuberculosis (Mtb) is the most infectious agent that caused PTB transferred by air droplets from one person to other. In the present epidemiological study, we aimed to record the total numbers and percentages of patients infected with PTB caused by Mtb during 12 months in AL-Najaf Governorate, Iraq. Methods: This study has been done in 2019 from January to the end of December in the north and south region of AL-Najaf Governorate, Iraq. Sputum of PTB-patients has been stained by Ziehl–Neelsen to Mtb diagnosis according to World Health Organization (WHO) recommendation. Results: We recorded 174 PTB-patients in AL-Najaf Governorate 2019; 89 male and 85 female; 101 and 73 in the north and south sections respectively. The age group 16-24 was the highest infected. Quarter two recorded the highest numbers of PTB-patients; 33 (60%) in the north section and 22 (40%) in the south section. Conclusion: There was low PTB incidence in AL-Najaf Governorate 2019 but the Youngers were the most susceptible to infection. Infection in the north section was higher than in the south section and there were no high differences between genders. Seasons have no high effect on the number of infections

2022

Assessment of ß-lactams and Carbapenems Antimicrobials Resistance in Klebsiella Oxytoca Isolated from Patients with Urinary Tract Infections in Najaf, Iraq

الباحثونYahya Abdulla, N، Abduljabbar Jaloob Aljanaby, I2, Hayder Hasan, T3 *,
المجلةArchives of Razi Institute,
مختصر البحث

Antimicrobial resistance is becoming an arising global issue. Until recent years, more than 50% of commercially available antibiotics were ß-lactam. Pathogenic bacteria which are resistant to antibiotics include all ß-lactams except for cephamycin and carbapenems. This study aimed to evaluate some ß-lactams and carbapenems antimicrobials resistance in Klebsiella oxytoca. In total, 177 urinary tract infection samples were collected for the purposes of the study. Isolates were identified using morphological features and routine biochemical testing. All isolates were tested for susceptibility to 11 antibiotics using the usual disc diffusion method. The result showed that 155 (87.57%) and 20 (11.29%) out of 177 collected urine samples were gram- negative bacterial isolates and gram-positive bacterial isolates, respectively. The findings also showed that there were two samples (1.12 %) with no growth. The results proved no susceptibility to Ampicillin, Cloxacillin, Ceftazidime, Penicillin, Piperacillin with a resistance rate of 100%. Keywords: Antibacterial, B-lactam, ESBL, UT

2022

Antibiotic. Susceptibilitpattern of E coli causing urinary tract infectionin pregnant women in alajaf province,Iraq

الباحثونThualfakar hayder hassan، israa abduljabaar jaloob aljanabi
المجلةUniversity of al kafeel
مختصر البحث

Antibiotic. Susceptibilitpattern of E coli causing urinary tract infectionin pregnant women in alajaf province,Iraq

2022

Antibiotic. Susceptibilitpattern of E coli causing urinary tract infectionin pregnant women in alajaf province,Iraq

الباحثونThualfakar hayder hassan، israa abduljabaar jaloob aljanabi
المجلةUniversity of al kafeel
مختصر البحث

Antibiotic. Susceptibilitpattern of E coli causing urinary tract infectionin pregnant women in alajaf province,Iraq

2018

Antimicrobial sensitivity pattern of pathogenic bacteria isolated from olderwomen with asymptomatic bacteriuria

الباحثونAhmed Abduljabbar Jaloob Aljanaby، Israa Abduljabbar Jaloob Aljanaby
المجلةBiomedical Research
مختصر البحث

Objectives: Asymptomatic bacteriuria is one of the most important silent diseases frequently infect women in worldwide. Aims: To determine the antimicrobial susceptibility pattern of pathogenic bacteria isolated from older women with asymptomatic bacteriuria.

2018

Profile of Antimicrobial Resistance of Aerobic Pathogenic Bacteria isolated from Different Clinical Infections in Al-Kufa Central Hospital –Iraq During period from 2015 to 2017

الباحثونAhmed Abduljabbar Jaloob Aljanaby1، Israa Abduljabbar Jaloob Aljanaby2
المجلةResearch J. Pharm. and Tech. 10(10): October 2017
مختصر البحث

ABSTRACT: Objectives: Resistance of antimicrobials by different pathogens is a dangerous problem in developing countries. Therefore we design this study to identify the most prevalent pathogenic bacteria that cause different infections in Al-Kufa Central Hospital – Iraq and determine the antibiotic susceptibility patterns of these pathogens. Methods: Five hundred and seventeen bacterial strains were isolated from different infections (urinary tract infections 171, burns infections 238, respiratory tract infection 55 and blood infection 53). Eleven antimicrobials disc were used to determine the antimicrobial sensitivity by disc diffusion method. Results: Pseudomonas aeruginosa was the most predominate bacteria (122 isolates) followed by K. Pneumoniae (96 isolates), E.coli (64 isolates), S. pyogenes (59 isolates), S. aureus (51 isolates), S. pneumoniae (48 isolates), Proteus. spp. (47 isolates) and Salmonella spp. (14 isolates). All bacterial strains were highly resistant to most antimicrobials with percentage between 90% to 100%.There were 459 bacterial strains (91.61%) were multidrug resistant. Conclusions: This study proved that the predominant bacteria of burns infections and urinary tract infections were P. aeruginosa followed by K. Pneumoniae. Gentamicin, Amikacin and Ciprofloxacin are a drug of choice for treatment of these infections.

2018

Antimicrobial sensitivity pattern of pathogenic bacteria isolated from olderwomen with asymptomatic bacteriuria.

الباحثونAhmed Abduljabbar Jaloob Aljanaby، Israa Abduljabbar Jaloob Aljanaby
المجلةF1000Research
مختصر البحث

Burn infections are one of the most common serious illnessesBackground: caused by pathogens, mainly by both gram-negative and gram-positive bacteria. The aim of this study was to detect of the prevalence of multi-drug resistant and extended-spectrum β-lactamase-producing (ESBL) bacteria isolated from inpatients with burn infection and the antimicrobials sensitivity patterns of all bacterial isolates during three years.

2018

Prevalence of some virulence associated-genes in methicillin resistance Staphylococcus aureus isolates from patients infected with septic arthritis and antimicrobial resistance patterns of these isolates

الباحثونIsraa Abduljabbar Jaloob Aljanaby، no
المجلةBIOSCIENCE RESEARCH
مختصر البحث

This is a Prospective study was done in Al-Najaf Governorate, Iraq during February 2015 to July 2016. Synovial fluid specimens were processed for bacterial culture according to the typical procedures, the prevalence of genes encoding of spa, v8 protease (SspA) and tsst-1 among methicillin resistant S. aureus associated with septic arthritis infection was determinants by PCR amplification. Antimicrobial susceptibility test was done using agar disk diffusion method. of the 400 synovial fluid samples, 65(16.25%) showed growth of gram positive and gram negative bacteria while 335(83.75%) of them were affected with aseptic type. The most frequent isolated gram positive bacteria was S. aureus 27 (41.53%) and all isolates were resistance to Methicillin. Twenty six (96.29%) strains were found to be spa+, 23(85.19%) strains were found to be v8 protease (SspA)+ and tsst-1 gene were found in 18 isolates (66.66%) . Vancomycin and Rifampicin show high rate of sensitivity compared with other antimicrobial drug.

2017

Profile of Antimicrobial Resistance of Aerobic Pathogenic Bacteria isolated from Different Clinical Infections in Al-Kufa Central Hospital –Iraq During period from 2015 to 2017

الباحثونAhmed Abduljabbar Jaloob Aljanaby، Israa Abduljabbar Jaloob Aljanaby
المجلةResearch J. Pharm. and Tech
مختصر البحث

Objectives: Resistance of antimicrobials by different pathogens is a dangerous problem in developing countries. Therefore we design this study to identify the most prevalent pathogenic bacteria that cause different infections in Al-Kufa Central Hospital – Iraq and determine the antibiotic susceptibility patterns of these pathogens.

2016

Prevalence of sea , hla and spa genes among methicillin resistance Staphylococcu saureus associated with Septic Arthritis Infection

الباحثونIsraaAbdAljabbarJaloobAljanaby، Abbas Shaker jawad AL-Muhana Hamed Allah AL Busisi
المجلةمجلة جامعة الكوفة لعلوم الحياة
مختصر البحث

In this study virulence determinants of methicillin-resistant Staphylococcus aureus (MRSA) from patient with septic arthritis infections of different age group were reported, emphasizing on the genes encoding sea ,hla and spa. 27 S. aureus strains were investigated for the presence of the genes of the sea ,hla and spa .27(100%) strains were found to be sea+ whereas the hla and spa genes were found in 26(96%) and 25(92.59%) of strains respectively. The finding that, among the investigated genes sea are present in all S. aureus Arthritis isolates encourages the development of strategies to specifically block the effect of this enterotoxin.

2015

SYNOVIAL MUCOSAL CYTOKINES AND CHAPEROKINE IN STAPHYLOCOCCUS AUREUS HUMAN SEPTIC A RTHRITIS

الباحثونIbrahim M S Shnawa، israa Aa Aljenaby, Hamad A Busisi and Iiyad F Al Aga
المجلةWorld Journal of Pharmaceutical Research
مختصر البحث

Human septic arthritis were clinically proven by the orthopedician in this team. S. aureus was reported in association of 27 neutrophilic synovitis out of 400 arthritis patients. Such patient infections induces local production of synovial cytokines TNF alpha, INF gamma, IL4 and the chaperokine heat shock protein HSP 70 to high levels than that of controls. The proinflammatory; TNF alpha, INFgamma, balanced by the anti-inflammatory IL4 and HSP70 representing the TH1/TH2 balance state. Hence, S. aureus initiate natural neutrophilic, humoral and cellular responses in the synovial compartment of the common mucosal immune system during the septic human arthritis.

2015

SYNOVIAL MUCOSAL CYTOKINES AND CHAPEROKINE IN STAPHYLOCOCCUS AUREUS HUMAN SEPTIC A RTHRITIS

الباحثونIbrahim M S Shnawa، israa Aa Aljenaby, Hamad A Busisi and Iiyad F Al Aga
المجلةWorld Journal of Pharmaceutical Research
مختصر البحث

Human septic arthritis were clinically proven by the orthopedician in this team. S. aureus was reported in association of 27 neutrophilic synovitis out of 400 arthritis patients. Such patient infections induces local production of synovial cytokines TNF alpha, INF gamma, IL4 and the chaperokine heat shock protein HSP 70 to high levels than that of controls. The proinflammatory; TNF alpha, INFgamma, balanced by the anti-inflammatory IL4 and HSP70 representing the TH1/TH2 balance state. Hence, S. aureus initiate natural neutrophilic, humoral and cellular responses in the synovial compartment of the common mucosal immune system during the septic human arthritis.

2007

Study the ability of Pseudomonas fluorescens to antagonize with some type of pathogenic bacteria and their sensitivity pattern against some antibiotics.

الباحثوناسراء عبد الجبار جلوب الجنابي
المجلةمجلة القادسية للعلوم الطبية
مختصر البحث

astudy was done to instigate the ability of Psudomonas fluorescens to antagonize and inhibit the growth of some kinds of pathogenic bacteria like pseudomonas aeruginosa,Ecoli,Shigella dysenteriae,klebsiella pnumoniae.staphylococcus aureus,streptococcus pyogenes, it was found that pseudomonas fluorescens grow in Kings Bbroth and nutrient broth had high efficiency to inhibit growth of all kinds of pathogenic by cross streaking method and to inhibit all kind of bacteria except Ecoli by disc agar method antimicrobial susceptibility test was done using Norflooxcin,Ciprofloxacin,Ceftazidime,Enrofloxacin showed high active against pseudomonas fluorescens while the bacteria was resistant toward Rifaampicin.Amikacin,Chloromphenicol,Amoxicillin and Nalidixiic acid

2006

Isolation and identification of aerobic pathogenic bacteria that causes conjunctivitis in hospital of Al-Furat Al Awsat in Kufa

الباحثوناسراء عبد الجبار جلوب الجنابي
المجلةمجلة القادسية لعلوم الطب البيطري
مختصر البحث

atotal of 20 samples of conjuctivitis were collected from patients were hospitalized in Kufa hospital and they were infected with other dieses.all patients were male aging 25-35years,during period between 20-6--20-7l2005.the results showed that the most bacteria that caused the conjunctivitis was Staphylococcus aureus 50.7% ,then Kllebsiella pnumoniae accounted for 30%and Streptococcus pyogenes which accounted for 15%.the antibiotics Tetracyclin,Gentamicin,Streptomycin was high active against Staphylococcus aureusandStreptococcus pyogenes which lead to inhibit their growth wheres the antibiotics Gentamycin,Chloromphenicol was high active agianst .Klebsiella pnumonae which also lead to inhibit its growth.

2006

Microbiological comparative study to pathogenic aerobic bacteria causing urinary tract infection to hospitalized and non-hospitalized patients in AL –Najaf general hospital

الباحثونمهدي حسين محيل ، اسراء عبد الجبار جلوب الجنابي
المجلةمجلة جامعة بابل
مختصر البحث

تم جمع 230 عينة ادرار من المرضى في مستشفى النجف العام شملت 145 عينة من المرضى الراقدين و 85 عينة من المرضى غير الراقدين وبعد اجراء العزل والتشخيص الاصولي للبكتريا وفحص الحساسية للمضدات الحياتية وتحليل ومقارنة النتائج وجد ان بكتريا E coli قد احتلت المرتبة الاولى بين البكتريا المرضية الهوائية المسببة لالتهاب المجاري البولية للمرضى الراقدين وبنسبة 25.5% وغير الراقدين بنسبة 68% وان الاناث هم اكثر عرضة للاصابة بة من الذكور وان المضاد الحياتي Cefotaxime ابدى فعالية عالية وبصورة رئيسية تجاة العزلات البكتيرية السالبة لصبغة كرام في حين ابدى المضاد الحياتي Cephalothin فعالية عالية تجاة العزلات الموجبة لصبغة كرام.

المحاضرات

3

Hemoflagellates

Medical Virology and Parasitology

immunology

immunology

pathogenic bacteria

medical microbiology -bacteria

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