Ukufa

البحوث المنشورة

Comparison of 1, 25-Dihydroxyvitamin D3 and Glutathione Reductase Levels in Thyroid Gland Patients

الباحث الأول: Tamara Ala`a Hussein

الباحثين الآخرين: NOORHAN KHALID SHAFEEQ NIBRAS ALAA HUSSAIN

المجلة: Pakistan Journal of Medical & Health Sciences

تاريخ النشر: None

مختصر البحث:

Background: Thyroid gland stands for a part of endocrine system in a human body, and it works to manufacture, store, and secrete hormones in the blood in order to reach the cells of the body, and has many important functions in the human bodyhea…

عرض المزيد

Determination of Glucagon-Like Peptide-1 and Dipeptidyl Peptidase-4 Levels in Diabetic Nephropathy Patients

الباحث الأول: , Tamara Ala`a Hussein

الباحثين الآخرين: Nibras Ala`a Hussein Noorhan Khalid Shafeeq

المجلة: Indian Journal of Public Health Research & Development

تاريخ النشر: None

مختصر البحث:

Background: Diabetic Nephropathy plays a key role in the function of kidneys to work for removing extra fluid and waste products from the body. The best way to prevent diabetic nephropathy is by maintaining a healthy lifestyle and treating diab… Background: Diabetic Nephropathy plays a key role in the function of kidneys to work for removing extra fluid and waste products from the body. The best way to prevent diabetic nephropathy is by maintaining a healthy lifestyle and treating diabetes and high blood pressure. Aim of the study was to locate the levels of Glucagon-Like Peptide-1 and Dipeptidyl Peptidase-4 in diabetic nephropathy patients and compare the results with the control group. Methods: The study involved 30 healthy controls and 30 diabetic nephropathy patients. Blood samples were collected from healthy controls and diabetic nephropathy patients after 12- 14 hours of fasting. The study was conducted between April 2015 and September 2015 in the diabetic & endocrinology center in Al-Sadder Medical City, Iraq. Whole blood used in determination of HbA1C. Serum was obtained from other part of blood that used in determination of FBG, Albumin, Urea, Creatinine, Total cholesterol, Triglyceride, high-density lipoprotein-cholesterol, GLP-1 and DPP-4. The levels of low-density lipoprotein-cholesterol and very low-density lipoprotein-cholesterol were analyzed by using Friedewald equation.. Results: The results showed significant elevation in FBG, HbA1C, GLP-1 and DPP-4 levels in diabetic nephropathy group comparing to control group. There was illustrated significant increased in TC, TG, LDL-c and VLDL-c in diabetic nephropathy group comparing to control group, while a significant decrease was noticed in HDL-c level in the patient group compared with the control group. Also, results of current study revealed a significant decrease in Albumin levels in diabetic nephropathy group comparing to control group. Moreover, the study showed a significant increase in Creatinine, Urea and Blood Pressure Levels in diabetic nephropathy group comparing to control group. Conclusion: there is significant association between Diabetic Nephropathy and raised FBS, HbA1C, GLP-1, DPP-4, TC, TG, LDL-c, VLDL-c, Creatinine, Urea levels and Blood Pressure and significant decrease in Albumin, HDL-c level in diabetic nephropathy group compared to control group. It is, therefore, recommended to use (DPP-4) inhibitors which stimulate insulin release and inhibit glucagon releaseng

عرض المزيد

The Effect of Calcium Oxide Nanoparticles on Liver Enzymes in White Rats

الباحث الأول: Tamara Ala`a Hussein

الباحثين الآخرين: Shurooq Wesam Al-Shaibani*, Wasnaa M. Abdulridha, Hayfaa Jaber Hussein

المجلة: | Journal of Global Pharma Technology|2019| Vol. 11| Issue 03 (Suppl.) |304-308

تاريخ النشر: None

مختصر البحث:

Calcium is the five elements that found on the crust of the earth. It`s the essential mineral for all organisms because the important role in the functions of the life cells , and its essential mineral for binding the bone and teeth by producing…

عرض المزيد

Determination celiprolol hydrochloride drug by used zero, first, second and third order derivative and peak area spectrophotometry method in its pure form and in pharmaceutical tablets

الباحث الأول: Tamara Ala`a Hussein

الباحثين الآخرين: Mohanad H Halboos, Aayad Ammar Sayhood

المجلة: 2nd International Science Conference

تاريخ النشر: None

مختصر البحث:

Abstract . An easy, specified, accurate, precise and reproducible quantitative analyses for determination of celiprolol hydrochloride drug by used used zero, first, second and third order derivative and peak area spectrophotometry method. The su…

عرض المزيد

Glucagon-like Peptide-1 Levels and Related Parameters in Rheumatoid Arthritis Patients Prone to Atherosclerosis

الباحث الأول: Tamara Ala`a

الباحثين الآخرين: Noorhan K. Shafeeq. Dept. of Chemistry / College of Education for Pure Science (Ibn AlHaitham)/Baghdad University Ban Mahmood Shaker Al-joda Dept.of Biochemistry /College of Medicine /Babylon University

المجلة: Ibn Al-Haitham Jour. for Pure & Appl. Sci.

تاريخ النشر: None

مختصر البحث:

Abstract The study aimed to estimate the role of glucagon-like peptide-1 (GLP-1) and visfatin as a novel pro inflammatory marker in Rheumatoid Arthritis (RA ) according to the activity scores of disease to assess the possibility of introducin…

عرض المزيد

GLP-1, GPCR Levels and their Relationshipwith Some Parameters in Nondiabetic Dyslipidaemia in Iraqi Patients

الباحث الأول: Tamara Ala`a

الباحثين الآخرين: Zeinab Moneb. Al-Rubaei, and Noorhan Khalid.Shafeeq* .

المجلة: Research Journal of Pharmaceutical, Biological and Chemical Sciences

تاريخ النشر: None

مختصر البحث:

Abnormalities in the Lipid and lipoprotein levels are common in the general population and are considered as very important risk- factors for cardiovascular disease .In this context the effect of cholesterol, which is one of the most clinically … Abnormalities in the Lipid and lipoprotein levels are common in the general population and are considered as very important risk- factors for cardiovascular disease .In this context the effect of cholesterol, which is one of the most clinically relevant lipids is very important. Aim of the present study was to determine the levels of GLP-1 and GPCR in non- diabetic dyslipidaemic patients and compare the results with the control group, which may be used as a novel biomarker to predict heart disease in these patients. The study was also aimed to find the relationship between GLP-1 and GPCR with lipid profile and glucagon in the patient group. The study involved 90 non-diabetic dyslipidaemia patients, with 90 healthy controls. The subjects were matched by age (35-50 years) and body mass index (BMI) (28 kg/m2). Blood samples were collected from healthy controls and dyslipidaemic patients after 12-14 hours of fasting. The study was conducted between January 2015– September 2015 in the Ibn- Al Naphes hospital in Baghdad province / Iraq .Diabetic patients were exclusion from this study. BMI were determined for all student groups.FBG, Lipid Profile ,glucagon, GLP-1, GPCR was determined in the control and patient groups. The results are expressed as mean ± SEM. Student ̓s t-test was used to compare the significance of the variation between dyslipidaemia and control groups. Results showed nonsignificant elevations in BMI, FBS, and HbA1c levels in the patient group compared with the control group. There was a significant elevation in TC, TG, LDL-c, and VLDL-c levels in the patient group compared with the control group, while a significant decrease was noticed in HDL-c level in the patient group compared with the control group .There was also a significant elevation in glucagon, while a highly significant elevation in GLP-1 and GPCR levels in the patient group when compared with the control group. A significant correlation was observed between GLP-1 with TC, TG, HDL-c, and GPCR in the patient group. There was also a significant correlation between GPCR with TC, TG and HDL-c in the patient group. From this study, it is concluded that a significant increase in GLP-1and GPCR levels, in addition to their correlation with TC, TG, HDL-c and glucagon in the patient group, compared to the control group indicate that these parameters could be used as a novel biomarker to predict heart disease in these patients in future.

عرض المزيد

Insulin and Glucagon Levels in Diabetic, Diabetic Neuropathy Patient`s

الباحث الأول: Tamara A. Hussein

الباحثين الآخرين: Zeinab M. Al-Rubaei

المجلة: Chemistry and Materials Research

تاريخ النشر: None

مختصر البحث:

Background: Diabetic neuropathy affects 30–50% of patients with diabetes mellitus. It encompasses several neuropathic syndromes, the commonest being distal symmetrical polyneuropathy or ‘diabetic peripheral neuropathy’ (DPN). Risk factors for DPN in… Background: Diabetic neuropathy affects 30–50% of patients with diabetes mellitus. It encompasses several neuropathic syndromes, the commonest being distal symmetrical polyneuropathy or ‘diabetic peripheral neuropathy’ (DPN). Risk factors for DPN include poor glycaemic control and drivers of macrovascular disease including hypertension.Objective: The study aimed to determination of insulin, glucagon levels in diabetic and diabetic neuropathy patient`s and compare the results with control group. Also, Insulin/Glu ratio calculated that may be used in early diagnosis of diabetic neuropathy.Subjects and Methods: ninety subjects were enrolled in this study with aged ranged (40-65) years and BMI with (30-35) Kg/m that divided into three groups as follows: group one (G1) consists of 30 healthy individuals as a control group, group two (G2) consists of 30 patients with diabetic and group three (G3) consists of 30 patients with diabetic and neuropathy as complication. ESC(Feet Mean), ESC(Hand Mean), ESC(Risk of neuropathies), FBS, insulin, Glucagon were determined. Also, HOMA-IR and insulin/Glu ratio were calculated.Results: The results of this study revealed highly significant differences in ESC (Feet Mean), ESC (Hand Mean) and ESC (Risk of neuropathies) between G2 and G3 comparing with G1 and in G3 comparing to G2. Results revealed a highly significant increased in FBS, insulin and HOMA-IR levels in G2 comparing to G1 and in G3 comparing to G2 and G1. Results, also, showed a high significant increased in glucagon levels in G2 and G3 comparing to G1 while no significant increased was found in G3 comparing to G2. Results, also, showed no significant reduction was found in In/Glu ratio in G2 comparing to G1, while a high significant elevation was observed in G3 comparing to G2 and G1.Conclusion: The conclusion could be drawn from this study that insulin and glucagon increased in patients with neurodiabetic when comparing to diabetic patients. Also, In/Glu ratio increased significantly in neurodiabetic patients when comparing to diabetic and control group that may be considered important marker in diagnosis of development of neuropathy risk.

عرض المزيد عرض البحث

GLP-1, DPP-4 and GPCR Levels in Diabetic and Diabetic neuropathy Patient`s

الباحث الأول: Tamara A. Hussein

الباحثين الآخرين: Zeinab M. Al-Rubaei

المجلة: Journal of Natural Sciences Research

تاريخ النشر: None

مختصر البحث:

Background: Neuropathy is a common disorder in DM patients which results from poor glycaemic control and long duration of diabetes. Higher body mass index, smoking, hypertension, hypercholesterolemia and hypertriglyceridemia are associated with the … Background: Neuropathy is a common disorder in DM patients which results from poor glycaemic control and long duration of diabetes. Higher body mass index, smoking, hypertension, hypercholesterolemia and hypertriglyceridemia are associated with the incidence of neuropathy. Objective: The aim of this study is to estimate glucagon like Peptide-1, DPP-4 and G-Protein coupled Receptor levels in diabetic and diabetic neuropathy and to compares the results with control group. Also, to find the correlation of GPCR with GLP-1 and DPP-4 in all studied groups.Subjects and Methods: ninety subjects were enrolled in this study with aged ranged (40-65) years and BMI with (30-35) Kg/m that divided into three groups as follows: group one (G1) consists of 30 healthy individuals as a control group, group two (G2) consists of 30 patients with diabetic and group three (G3) consists of 30 patients with diabetic and neuropathy as complication. ESC(Feet Mean), ESC(Hand Mean), ESC(Risk of neuropathies), HbA1C, GLP-1, DPP-4 and GPCR were determined.Results: The result showed highly significant elevation in HbA1C levels in patients groups comparing to control group. Results, also a highly significant elevation in GLP-1 and DPP-4 levels in G2 comparing to G1, and in G3 comparing to G2 and G1 were noticed. A highly significant elevation in GPCR levels in G2 comparing to G1and G3, while no significant increased noticed in G3 comparing to G2. A high significant positive correlation was found between GLP-1 and DPP-4 in G1, while highly significant negative correlation was found in G2 and G3. A high significant positive correlation was observed between GLP-1 and GPCR in G1. Moreover, No significant positive correlation was observed in G2, but a significant positive correlation was observed in G3. High significant negative correlation was found between GPCR and DPP-4 in G1 and G2, while a high significant positive correlation was found in G3. Conclusion: the conclusion is obtained from this study that GLP-1and GPCR have important role in development of neuro injury in neurodiabetic patients. Also, correlation was found between GPCR with GLP-1 and DPP-4.

عرض المزيد عرض البحث

Atherogenic Index of Plasma Levels in Patients with Diabetic and Neurodiabetic

الباحث الأول: Tamara A. Hussein

الباحثين الآخرين: Dr. Zeinab M. Al-Rubaei

المجلة: Journal of Kufa for Nursing Science

تاريخ النشر: None

مختصر البحث:

Objective: To determined the levels of lipid profile (TC, TG, HDL-c, LDL-C, VLDL) in diabetic and diabetic neuropathy patients and compare the results with control group. Also, to compare Atherogenic Index of Plasma (AIP) levels in these groups that…

عرض المزيد

EVALUATION THE EFFECT OF THE ABO GROUPING ON THE ERUPTION OF WISDOM TOOTH

الباحث الأول: Tamara A. Hussein

الباحثين الآخرين: Bushra Habeeb Al-Molla, Haifaa Jaber Hussian

المجلة: International Journal of Recent Scientific Research

تاريخ النشر: None

مختصر البحث:

Eruption is defined as the movement of the tooth from its site of development in alveolar bone to the occlusal plane in the oral cavity.The tooth eruption is a complex and tightly regulated process which is divided into five stages. The ABO blood g…

عرض المزيد

Study The Relationship Between ABO Blood Groups And Gingivitis Disease

الباحث الأول: Tamara Ala`a Hussein

الباحثين الآخرين: Bushra Habeeb, Hayfa`a Jaber

المجلة: Journal of Kufa for Nursing Science

تاريخ النشر: None

مختصر البحث:

Objectives : Design this study to determine whether there was a relationship between gingival diseases and ABO blood groups . Methods : Data were collected from 1 2 9 subjects who were randomly selected from students referred to the Faculty of Denti…

عرض المزيد

Study the some concentrations of Immunoglobulins IgG ,IgM ,IgA in Psoriasis Patients

الباحث الأول: Tamara Ala`a Hussein

المجلة: Journal of Kerbala University

تاريخ النشر: None

مختصر البحث:

This study designs to study the effect Psoriasis disease on the concentration of some immunoglobulins in human. The study divided into two groups : psoriasis patients group including 20 Randomly individuals of both sexes with different ages. a…

عرض المزيد

Micro Determination Study and Organo physical properties Of Resorcinol with Thiamine in the Presence of Potassium Dichromate.

الباحث الأول: Tamara .A. Hussein

الباحثين الآخرين: Hussain .J. Mohammed

المجلة: Kufa Journal for Nursing Sciences

تاريخ النشر: None

مختصر البحث:

Objective: This study aims to estimate Resorcinol (3- hydroxy phenol). Methodology : The study was through the development of a simple and high sensitivity and selectivity to estimate Resorcinol (3- hydroxy phenol) and The method is based on the rea…

عرض المزيد

Insulin effect on inflammatory response compared to sulfonylurea in diabetes mellitus patients

الباحث الأول: Tamara A. Al-ubaidy

الباحثين الآخرين: Nijoud. F. AL-sarrag , Zohair. I. AL-mashhadani

المجلة: Diala Journal

تاريخ النشر: None

مختصر البحث:

This study was designed to state the ground stone of the role of the insulin as anti-inflammatory agent in different inflammation process. Fasting venous blood samples were taken from 150 subjects of which 50 patients with type 1 diabetes, …

عرض المزيد

تمارا علاء حسين العبيدي

الملف الشخصي

الاهتمامات البحثية

البحوث المنشورة

Comparison of 1, 25-Dihydroxyvitamin D3 and Glutathione Reductase Levels in Thyroid Gland Patients

Determination of Glucagon-Like Peptide-1 and Dipeptidyl Peptidase-4 Levels in Diabetic Nephropathy Patients

The Effect of Calcium Oxide Nanoparticles on Liver Enzymes in White Rats

Determination celiprolol hydrochloride drug by used zero, first, second and third order derivative and peak area spectrophotometry method in its pure form and in pharmaceutical tablets

Glucagon-like Peptide-1 Levels and Related Parameters in Rheumatoid Arthritis Patients Prone to Atherosclerosis

GLP-1, GPCR Levels and their Relationshipwith Some Parameters in Nondiabetic Dyslipidaemia in Iraqi Patients

Insulin and Glucagon Levels in Diabetic, Diabetic Neuropathy Patient`s

GLP-1, DPP-4 and GPCR Levels in Diabetic and Diabetic neuropathy Patient`s

Atherogenic Index of Plasma Levels in Patients with Diabetic and Neurodiabetic

EVALUATION THE EFFECT OF THE ABO GROUPING ON THE ERUPTION OF WISDOM TOOTH

Study The Relationship Between ABO Blood Groups And Gingivitis Disease

Study the some concentrations of Immunoglobulins IgG ,IgM ,IgA in Psoriasis Patients

Micro Determination Study and Organo physical properties Of Resorcinol with Thiamine in the Presence of Potassium Dichromate.

Insulin effect on inflammatory response compared to sulfonylurea in diabetes mellitus patients

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كيمياء حياتيه

كيمياء حياتيه

كيمياء حياتيه

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كيمياء حياتيه

كيمياء حياتيه

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كيمياء حياتيه

Aliphatic Hydrocarbons / Alkanes Medical Chemistry

Aliphatic Hydrocarbons / Alkenes Medical Chemistry

Aliphatic Hydrocarbons / Alkynes Medical Chemistry

Alkyl Halides Medical Chemistry

Alcohols Medical Chemistry

Phenols Medical Chemistry

Aromatic Hydrocarbons Medical Chemistry

Ethers Medical Chemistry

Thiols Medical Chemistry

Carbohydrates Medical Chemistry

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