EFFECT OF METHANOL EXTRACT OF ALTHAEA OFFICINALIS L.
FLOWERS ON ESTROGEN AND OVARY OF RATS
الباحث الأول:
Bushra Abbas Al–Zubaide
الباحثين الآخرين:
Shaimaa Mahdi A. Jawad, Zainab Jawad Naki Busaid and
Wijdan Kamal NoorAl-Shalan
المجلة:
Biochem. Cell. Arch. Vol. 18, No. 1, pp. 813-817, 2018
تاريخ النشر:
None
مختصر البحث:
ABSTRACT : The present study aimed to investigate the effectof methanol extract of Althaea officinalis flowerson
serum estrogen and ovary in mature female albino rats. Twenty mature female albino rats were randomly divided into
two groups, ten for…
ABSTRACT : The present study aimed to investigate the effectof methanol extract of Althaea officinalis flowerson
serum estrogen and ovary in mature female albino rats. Twenty mature female albino rats were randomly divided into
two groups, ten for each group. Control Group, rats were normal and untreated. Treated group, were normal rats
administrated orally with 2 ml methanol extract of Althaea officinalis flowers at 500 mg/kg, daily for 14 days. Blood
samples were taken for estrogen assays. while ovaries were used for the histological studies. The results showed there
was significant reduction (P< 0.05) in estrogen of the treated rats when compared with the control and there were
remarkable noted in the histology of ovary of treated group. The results suggest thatAlthaeaofficinalis has female antifertility
properties, possibly acting via inhibition of estrogen secretion, resulting from the interference of secondary
metabolic (phytoestrogen) of the plant with physiology reproductive of rats.