رؤى شلتاغ نايل الرديني

اللقب العلمي: أستاذ مساعد

الكلية: العلوم

القسم: التحليلات المرضية

[email protected]

الملف الشخصي

السيرة العلمية (Academic Profile)
المعلومات الشخصية

الاسم: رؤى شلتاغ نايل
الحالة الاجتماعية: متزوجة ولدي طفلان
الاختصاص العام: علوم الحياة
الاختصاص الدقيق: الأحياء المجهرية / التحليلات المرضية

المؤهلات العلمية

بكالوريوس علوم حياة – كلية العلوم – جامعة الكوفة – 2004–2005

ماجستير علوم حياة – 2010–2012

دكتوراه علوم حياة – 2015–2018

تمت مناقشة أطروحة الدكتوراه بتاريخ 4 / 9 / 2018.

الألقاب العلمية

مدرس – بتاريخ 11 / 8 / 2018

أستاذ مساعد – بتاريخ 17 / 5 / 2022

الوظيف…

عرض المزيد

الاهتمامات البحثية

الأحياء المجهرية الطبية
اللقاحات البكتيرية
تشخيص مايكروبي

البحوث المنشورة

Study of Microbial Infections and Some Immunological Parameters among Covid-19 in ICU Patients in Najaf Governorate, Iraq

الباحث الأول: SH.R

المجلة: Archives of Razi Institute

تاريخ النشر: 12 إبريل، 2022

مختصر البحث:

The present study aimed to investigate some microbial infections and immunological parameters associated with Covid-19 patients admitted to the intensive care unit (ICU) of Al-Amal Specialized Hospital in AL-Najaf Governorate during February and… The present study aimed to investigate some microbial infections and immunological parameters associated with Covid-19 patients admitted to the intensive care unit (ICU) of Al-Amal Specialized Hospital in AL-Najaf Governorate during February and March 2021. The study included 50 patients who were assigned to two groups: 20 patients aged ≤70 years and 30 patients aged ≥70 years. The method of microbial culture was adopted to isolate bacteria and yeasts by collecting sputum specimens and oral swabs from patients and cultivating them on diagnostic media and then confirming the diagnosis by Vitek. Moreover, serum samples were collected from patients’ blood to diagnose fungal infections. Thereafter, some immunological criteria were assessed, including Covid-19 diagnosis by measuring Immunoglobulin M (IgM) and IgG, as well as examining the concentration of cytokines (Interleukin 6 (IL-6) and IF ) using the enzyme-linked immunosorbent assay (ELISA) method. The results demonstrated that bacterial species Streptococcus pneumonia (n=5; 25%), Haemophilus Influenzae (n=7; 35%), and Moraxella catarrhalis (n=3; 15%) were isolated from the first group of patients (≤70 years). The recorded data pointed out that Streptococcus pneumonia (n=10; 33.3%), Streptococcus pyogenes (n=5; 16.6%), Streptococcus viridans (n=1; 3.3%), Haemophilus Influenzae (n=6; 20%), Mycobacterium tuberculosis (n=2; 6.6%), and Pseudomonas aeruginosa (n=2; 6.6%) were the isolated and identified microorganisms in the second age group (≥ 70 years). The results revealed that the isolated yeast from the first age group was Candida albicans (n=5; 25%) and Candida glabrata (n=3; 10%), while in the second age group, 1 (3.3%) Candida albicans was isolated. The results of this study proved that 30% and 10% of patients in the first and second age groups had invasive pulmonary aspergillosis co-infection by detecting Galactomannan (GM) in the blood serum (1.05±0.59, 1.25±0.38), respectively. The results indicated that IgM and IgG levels in the serum of patients in the first age group were 11.42±6.82 and 0.47±6.82, respectively. Moreover, the levels of IgM and IgG in the second age group were 14.84±9.21 and 0.12±0.11, respectively. Furthermore, IFɤ and IL6 levels were 98.37±65.70, and 146.12±46.35 in the first group, while IFɤ and IL6 were obtained at 110.69±47.60 and 133.28±116.94 in the second group, respectively. Elderly patients with severe COVID-19 are more frequently admitted to ICUs since the proportion of severe cases and comorbidities caused by a weakened immune system is higher among this age group. Secondary bacterial infections can also occur, especially Gram-negative bacteria which are among the most significant public health problems worldwide. Moroever, aspergillosis may infect patients hospitalized with COVID-19 and lead to death.

عرض المزيد عرض البحث

Anticancer Activity Assay of Nano-Fractional Compounds that Purified from Soil Actinomycetes

الباحث الأول: SUHAD MOHAMMAD

الباحثين الآخرين: RUAA SHILTAGH

المجلة: Archives of Ecotoxicology

تاريخ النشر: None

مختصر البحث:

Cancer remains a global problem of health, and has been recorded as one of the causes of death after heart disease Natural products from plants, the environment and microorganisms are leveraged for the purpose of fighting cancer. Actinobacteria have…

عرض المزيد عرض البحث

Molecular Characterization of Waa Genes (waaA, waaC, wamB, wabG) Participate in Core Biosynthesis in P.mirabilis LPS

الباحث الأول: Ruaa SH RedeinyRuaa SH Redeiny

الباحثين الآخرين: Mayyada F. Darweesh

المجلة: International Journal of Psychosocial Rehabilitation

تاريخ النشر: None

مختصر البحث:

LPS is a potential Proteus virulence factor that plays a key role in pathogenesis as well as in stimulating innate immune response. The structure of lipopolysaccharide differs from one bacterium to another, dependent on enzymes and gene products t…

عرض المزيد

Liposomal-lipopolysaccharide vaccine extracted from Proteus mirabilis induces moderate TLR4 and CD14 production

الباحث الأول: Ruaa SH.

الباحثين الآخرين: Mayyada F. Darweesh* , Mohauman M. Al-Rufaie

المجلة: Current Issues in Pharmacy and Medical Sciences

تاريخ النشر: None

مختصر البحث:

Proteus mirabilis is a common cause of recurrent urinary tract infections in individuals with functional or structural abnormalities. It also forms bladder and kidney stones. Lipopolysaccharide (LPS) is a potential Proteus virulence factor that pl… Proteus mirabilis is a common cause of recurrent urinary tract infections in individuals with functional or structural abnormalities. It also forms bladder and kidney stones. Lipopolysaccharide (LPS) is a potential Proteus virulence factor that plays a key role in pathogenesis, as well as in stimulating innate immune response. Therefore, this study aimed to extract LPS from a highly resistant isolate and incorporate it in a delivery system (liposome) to stimulate an immune response against virulent pathogens. In the work, 50 isolates of P. mirabilis were taken from 200 urine specimens obtained from recurrenturinary tract infections (UTI) of patients of AL-Sadar Hospital. Specimens were cultured on specific media, and then bacterial isolates were identified via morphological, biochemical and Vitek-2 systems. The results showed that P. mirabilis was expressed in 11 (22%), 30 (60%) and 9 (18%) recurrent UTI, kidney stone and catheter samples, respectively. All isolates were assessed through antibiogram testing, with the results revealing that most isolates were multidrug resistant to more than 3 classes of antibiotics. Herein, P. mirabilis NO 50 revealed particularly high resistance, so it was chosen for LPS extraction. Lethal dose 50 (LD50) observations indicated that a live suspension of P. mirabilis was at 4.5×107 CFU/ml, while LPS was at 270 μg/ml. LPS was used as an immunogenic to stimulate the immune system through injecting Rats intraperitoneally (I.P.) with 1 ml of LD50%. Subsequently, the efficiency of immunogenes in stimulating the immune response was evaluated by determining the Toll-like receptor and CD14 levels. The results indicate that LPS incorporated in the Liposome released moderate levels of Toll-like receptors-4 (TLR4) that enabled the immune system to clear pathogens. The LPS+ complete Freund’s adjuvant (CFA) and LPS vaccinated groups recorded hyper production for TLR4 (52.2 and 40.9 pg/ml, respectively), this was followed by liposome (LIP) and bacterial suspension (11 and 20.5 pg/ml, respectively) in ranking effectiveness. This study reveals a mean of CD14 that was higher in both LPS and LPS+CFA and moderate in LPS+LIP, in comparison with control and liposome groups. In conclusion, LPS-Liposomes are a promising nanomedicine for modulating the hyper response of LPS. This may lead to tissue inflammation but appeared beneficial in stimulating the immune response at moderate levels so as to eradicate infection without tissue damage

عرض المزيد عرض البحث

he Prevalence Study of Viral Hepatitis in AL-Najaf AL-Ashraf Province

الباحث الأول: Ruaa Sheltagh Nile

الباحثين الآخرين: *, Doaa Amer Kadhim and Mohammed Abduaali Mohsin

المجلة: International Journal of Current Research in Biosciences and Plant Biology

تاريخ النشر: None

مختصر البحث:

This study was conducted to detect the prevalence of Hepatitis C virus and Hepatitis B virus of infected Patients. The study was carried out in the period from January (2016) to December (2016). The study included 420 hepatitis C and B virus suspe…

عرض المزيد

Antibiotic Resistance Pattern of Escherichia coli Isolated from Urinary Tract Infections

الباحث الأول: Ruaa Sheltagh Nile

المجلة: International Journal of Current Research in Biosciences and Plant Biology

تاريخ النشر: None

مختصر البحث:

Forty seven of Gram-negative-lactose sugar fermenting bacteria grown on MacConkey agar was isolated from UTI collected from Al-Sadar Medical City and AL-Zahraa Hospital Education in Al-Najaf province, during 15-7-2013 to 20-10-2013. The bacterial is…

عرض المزيد

Virulence Factors of Pseudomonas aeruginosa Isolated from Wound and Burn Infections

الباحث الأول: Ruaa Sheltagh Nile

الباحثين الآخرين: Lina A. Hassan and EhabYehiea Jabber

المجلة: International Journal of Current Research in Biosciences and Plant Biology

تاريخ النشر: None

مختصر البحث:

Fifty number of Gram-negative non-fermenting lactose bacteria grown on MacConkey agar were isolated from burns and wounds of the samples collected from Al-Sadar Medical City in Al- Najaf Province, during 10/9/2010-10/12/2010. The bacterial isolat…

عرض المزيد

Screening of Some Bacterial and Fungal Infections in Neutropenic Cancer Patients in Al-Najaf Governorate, Iraq

الباحث الأول: RUAA SH

الباحثين الآخرين: S. Suhad Mohammed1 G.F. Abd Al-Hussan

المجلة: Iranian Journal of War & Public Health

تاريخ النشر: 3 مايو، 2023

مختصر البحث:

ims: Ultrasound is the initial imaging modality for the detection of salivary gland tumors. There is an argument for evaluating multiple characteristics for predicting tumors using this imaging modality because no single sonographic feature is adequ…

عرض المزيد عرض البحث

المحاضرات

Transmission of microorganisms احياء مجهرية طبية

PATHOGENECITY احياء مجهرية طبية

Pathogenicity of Microbe in Digestive System احياء مجهرية طبية

MICROBES THAT INFECTED NERVOUS SYSTEM احياء مجهرية طبية

Pathogenicity of Virus and Fungi احياء مجهرية طبية

History of microorganism discovery اساسيات احياء مجهرية

الأخبار والإعلانات

المناقشة

النوع: الأخبار

التاريخ: 3 أكتوبر، 2018

التفاصيل:

جرت مناقشة طالبة الدكتوراه في يوم الثلاثاء المصادف 4/9/2018 وكانت لجنة المناقشة تتالف من د. محمد حسن رئيسا , د. احلام نعيم عضوا , د. ابراهيم عبد المجيد ,د. عدي متعب عضوا ,د. اثير باسل عضوا والدكتورة ميادة فرحان مشرفا وعضوا

عرض المزيد

مناقشة

النوع: الأخبار

التاريخ: 30 أغسطس، 2021

التفاصيل:

تم اشتراكي في مناقشة بحوث التخرج فس قسم التحليلات المرضية لعام 2019-2020 و 2020-2021

عرض المزيد

ترقية

النوع: الأخبار

التاريخ: 5 نوفمبر، 2024

التفاصيل:

تم ترقيتي الى استاذ مساعد في 17-5-22

عرض المزيد

مناقشة طالب دكتوراه

النوع: الأخبار

التاريخ: 7 مارس، 2026

التفاصيل:

تمت مناقشة طالب ماجستير في يوم 3-7-2025

عرض المزيد

رؤى شلتاغ نايل الرديني

رؤى شلتاغ نايل الرديني

الملف الشخصي

الاهتمامات البحثية

البحوث المنشورة

Study of Microbial Infections and Some Immunological Parameters among Covid-19 in ICU Patients in Najaf Governorate, Iraq

Anticancer Activity Assay of Nano-Fractional Compounds that Purified from Soil Actinomycetes

Molecular Characterization of Waa Genes (waaA, waaC, wamB, wabG) Participate in Core Biosynthesis in P.mirabilis LPS

Liposomal-lipopolysaccharide vaccine extracted from Proteus mirabilis induces moderate TLR4 and CD14 production

he Prevalence Study of Viral Hepatitis in AL-Najaf AL-Ashraf Province

Antibiotic Resistance Pattern of Escherichia coli Isolated from Urinary Tract Infections

Virulence Factors of Pseudomonas aeruginosa Isolated from Wound and Burn Infections

Screening of Some Bacterial and Fungal Infections in Neutropenic Cancer Patients in Al-Najaf Governorate, Iraq

المحاضرات

Transmission of microorganisms احياء مجهرية طبية

PATHOGENECITY احياء مجهرية طبية

Pathogenicity of Microbe in Digestive System احياء مجهرية طبية

MICROBES THAT INFECTED NERVOUS SYSTEM احياء مجهرية طبية

Pathogenicity of Virus and Fungi احياء مجهرية طبية

History of microorganism discovery اساسيات احياء مجهرية

Normal Flora (Commensals) اساسيات احياء مجهرية

Shape and Structure of Bacteria اساسيات احياء مجهرية

Reproduction of Bacteria اساسيات احياء مجهرية

Cellular respiration اساسيات احياء مجهرية

Applications of Microbiology اساسيات احياء مجهرية

الأخبار والإعلانات

المناقشة

مناقشة

ترقية

مناقشة طالب دكتوراه