Impactofplasmaneutrophilgelatinase-associatedlipocalinelevelon earlyoutcomeofapatientwithST-segmentelevationmyocardial infarction
الباحث الأول:
SadiqJ.Al-Muhana1,
الباحثين الآخرين:
ZahraaAbdulaaliAl-Mudhafar*1,RawaaBahlool2,NajahRHadi1,SafaaImran Musa3
المجلة:
InternationalJournalofResearchinPharmaceuticalSciences
تاريخ النشر:
None
مختصر البحث:
Inpatientswiththeatheroscleroticarteries,Neutrophilgelatinase-associated lipocaline (NGAL) may play a part in vascular remodeling and the instability of atherosclerotic plaques. Patients with angiographically documented coronaryarterydiseasehavesign…
Inpatientswiththeatheroscleroticarteries,Neutrophilgelatinase-associated lipocaline (NGAL) may play a part in vascular remodeling and the instability of atherosclerotic plaques. Patients with angiographically documented coronaryarterydiseasehavesigniicantlyhigherlevelsofserumNGALcompared with persons with normal coronary arteries. This study aims to determine theshorttermprognosticvalueofNGALserumlevelsinapatientwithacute ST-segment elevation myocardial infarction. This is study enrolled twenty patients with acute ST-elevation myocardial infarction (STEMI) and twenty healthy subjects as control. Serum NGAL level was compared between the patients and control and then correlated with early outcome of the patients. TherewasasigniicantelevationofserumNGALinSTEMIpatientsCOMARED with control, and signiicant relationship was observed between admission serum NGAL early complications and mortality. High NGAL level associated with poor outcome in STEMI patients and can be use as initial indicator for closemonitoringofhigh-riskpatients.
