Quantitative Assessment of Serum‐Specific IgE in the Diagnosis of
Echinococcus granulosus
الباحث الأول:
Fatima S. Kadhim1
الباحثين الآخرين:
Rasha A. Noori2
المجلة:
Egyptian Academic Journal of Biological Sciences
C. Physiology & Molecular Biology
تاريخ النشر:
5 أغسطس، 2023
مختصر البحث:
A total of 50 serum samples were collected from patients with Echinococcus granulosus and 38 serum samples from healthy humans were taken from the Al-Furat AL-Awsat Hospital, Maternity and Children Teaching Hospital and Al-Diwaniyah Teac…
A total of 50 serum samples were collected from patients with Echinococcus granulosus and 38 serum samples from healthy humans were taken from the Al-Furat AL-Awsat Hospital, Maternity and Children Teaching Hospital and Al-Diwaniyah Teaching Hospital in Al-Diwaniyah and from Specialized Hospital for Gastroenterology and Hepatology in AL-Najaf for the period from November 2022 to April 2023. The test was performed on 5 ml of venous blood, which was collected from each sample for an Enzyme-linked immunosorbent assay (ELISA) test to detect Echinococcosis IgE. The clinical assessment of the 50 patients (who confirmed to have Echinococcosis after giving positive results by Enzyme-linked immunosorbent assay (ELISA) was revealed that the frequency of distribution of patients according to sex was (74%) females and (26%) males. The differences between females and males were statistically significant (P < 0.05, P-value= 0.001). The estimated incidence of Echinococcosis increased in the 21-40 years age group, with a significant difference (P < 0.05) in comparison with the other groups. The Distribution of Hydatid Cysts according to the site of the infection was the high rate of infection in the liver compared with other organs. The concentration level of IgE was increased in patients compared with the control, with a significant difference at (P ≤ 0.05) while the level of IgE was decreased after the surgery compared with the before the surgery in patients with a significant difference at (P ≤ 0.05). The levels of IgE concentrations in patients according to the location of the cyst were the highest level in the liver.
