Mucin2 and Lipid Profile Estimation in Giardia
Lamblia Infected Patients: A Case-control Study
الباحث الأول:
Raad Abdulameer Alasady
الباحثين الآخرين:
Rana Talib Al-Nafakh
, Thanaa Shams Aldeen Al-Turahi
,Ahmed Jasim Tayyeh
, Ekhlas Sabah Hassan
المجلة:
Journal of Communicable Diseases
Volume 54, Issue 2 - 2022, Pg. No. 55-60
تاريخ النشر:
None
مختصر البحث:
Introduction: Globally, Giardia duodenalis (G. lamblia) is a protozoan
parasite that has the ability to cause sporadic or epidemic infectious
diarrhoea. Giardia infection is a crucial cause of waterborne and
foodborne disease, outbreaks in the…
Introduction: Globally, Giardia duodenalis (G. lamblia) is a protozoan
parasite that has the ability to cause sporadic or epidemic infectious
diarrhoea. Giardia infection is a crucial cause of waterborne and
foodborne disease, outbreaks in the daycare centre, and international
travel-related infection. This study aimed to evaluate the effects of
Giardia lamblia infection on serum MUC2 and lipid profile.
Patients and Methods: From March to April 2021, a case-control study
was conducted on 48 patients with giardiasis who attended AL-Hakeem
Hospital in Najaf Province in Iraq and 24 healthy adults as a control
group. Stool examinations were done using standard techniques for
the identification of the parasitic infection.
Results: The results showed a significantly higher concentration (130.57
± 4.04 ng/ml, and 130.11 ± 3.6 ng/ml) (p < 0.05 of MUC2 in G. lamblia
infected patients (males and females) in comparison to the individuals
of the control group. In addition, significantly higher concentrations (p <
0.05) of cholesterol, VLDL, TG, and LDL were found in comparison to the
control individuals, whereas the concentration of HDL was significantly
lower (p < 0.05 in patients infected with G. lamblia as compared to the
control group.
Conclusion: The current study revealed that MUC2 and lipid profile are
valuable biomarkers that help in the diagnosis of G. lamblia parasite
infection.
