The role of CSF-CRP in diffrentation between bacterial from nonbacterial
meningitis.
الباحث الأول:
Qasim Mohammed Hashim
الباحثين الآخرين:
a Hidhab Jawad Muhssin, Nadia Adbulhussein Salish, Jasim M Hashim, Alaa
Maan Johny, Alaa Jumaah Manji Nasrawi *
المجلة:
Current Pediatrics research
تاريخ النشر:
None
مختصر البحث:
Background: Meningitis is one of dangerous disease in children and the differentiation between acute
bacterial and non- bacterial meningitis (particularly viral meningitis) is so important because they
differ in their prognosis and treatment. CSF …
Background: Meningitis is one of dangerous disease in children and the differentiation between acute
bacterial and non- bacterial meningitis (particularly viral meningitis) is so important because they
differ in their prognosis and treatment. CSF culture and gram stain is ideal for diagnosis but it is
coasty and time consuming,so looking for biological markers like CSF-CRP to simplify the accuracy of
initial diagnosis of acute meningitis.
Objective: To find out the significance of CSF-CRP in patients with bacterial meningitis.
Methods: Cross sectional study performed in Babylon teaching hospital on 45 clinically suspected
meningitis patients were evaluated for Serum CBC, CRP, Lumbar puncture and CSF examination.
Immediately after hospital admission, lumbar puncture and Cerebrospinal Fluid (CSF) examination
(bacteriological, cytological and chemical) were done for all patients.
Results: CSF-CRP level was remarkably increased in bacterial meningitis (mean 6.59 ± 5.81 mg/l) in
comparison with non-bacterial meningitis (mean 1.14 ± 2.36 mg/l), (p<0.001). There are positive
relations with WBC and CRP in non-bacterial and bacterial meningitis but this correlation become
greatly significant with bacterial meningitis positive groups.
Conclusion: This study shows that CSF-CRP can be used for early diagnosis of bacterial meningitis
and may be a helpful association in differentiation bacterial and non-bacterial meningitis with CBC
and serum CR
