مختصر البحث:
This study reports the synthesis of the novel azo-Schiff base, 4,4'-(((3Z,3'Z)-(((2E,4E))-3-((4- (trifluoromethyl)phenyl)diazenyl)pentane-2,4-dione) bis (azaneylylidene)) bis (1,5-dimethyl-2-phenyl-2,3-dihydro- 1H-pyrazol-4-yl-3-ylidene)) bis azaney…
This study reports the synthesis of the novel azo-Schiff base, 4,4'-(((3Z,3'Z)-(((2E,4E))-3-((4- (trifluoromethyl)phenyl)diazenyl)pentane-2,4-dione) bis (azaneylylidene)) bis (1,5-dimethyl-2-phenyl-2,3-dihydro- 1H-pyrazol-4-yl-3-ylidene)) bis azaneylylidene)) bis (3-hydroxybenzenesulfonamide), (ligand), through three steps, along with its metal complexes. The final step involved condensing the new azo and Schiff base molecules ((E)-3- ((4-(trifluoromethyl)phenyl)diazenyl)pentane-2,4-dione) and ((Z)-3-((4-methoxy-2-nitrophenyl)imino)-1,5- dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-4-amine), respectively. All new compounds were characterized using various spectral techniques, including C.H.N. elemental analysis, Fourier Transform Infrared spectroscopy (FTIR), ultraviolet-visible (UV-Vis) spectroscopy, proton nuclear magnetic resonance (1H-NMR), and mass spectrometry. Additionally, mole ratio analysis determined the complexes' composition [M: L] with several metals, such as Co(II), Ni(II), Cu(II), Zn(II), Cd(II), Hg(II), and Au(III). These ions chelated with the ligand in a 1:1 molar ratio, and all displayed octahedral geometry except for the Au(III) complex, which exhibited a square planar shape. All complexes are nonelectrolytes with no conducting species, except the Au(III) complex, which is a 1:3 electrolyte. This could explain the electrolytic behavior of the metal complexes. Furthermore, the biological activities of the Au complex against various organisms, including Gram-positive G(+ve) Staphylococcus aureus, Gram-negative G(-ve) Escherichia coli, and fungi such as Aspergillus niger and Aspergillus flavus are documented.
