A COMPARISON OF KINETIC STUDIES OF KAOLIN CLAY AND RICE HUSKS FOR CIPROFLOXACIN ADSORPTION
الباحث الأول:
MAJIDA HAMEED KHAZAAL
الباحثين الآخرين:
HAYFAA JASIM SINBAH
المجلة:
International Journal of Applied Pharmaceutics
تاريخ النشر:
3 إبريل، 2023
مختصر البحث:
Objective: to compare the absorption of this drug on two surfaces of Iraqi kaolin and rice husks, which are considered environmentally friendly
natural products and available locally.
Methods: Ciprofloxacin adsorption from an aqueous solution was …
Objective: to compare the absorption of this drug on two surfaces of Iraqi kaolin and rice husks, which are considered environmentally friendly
natural products and available locally.
Methods: Ciprofloxacin adsorption from an aqueous solution was studied with respect to contact time, pH, and concentration. 30 min was
determined to be the equilibrium time. Increasing the drug concentration on both adsorbents increased the adsorption rate, and the data fit well
into a pseudo-second-order model. The solution concentration was analysed by UV-visible spectroscopy. Then the amount of adsorption was
calculated, as well as the study of the reaction kinetics for both surfaces. The rice husk adsorbent showed faster removal with higher uptake than
the Kaolin clay in both SGF and SIF solutions.
Results: The adsorption isotherms of type (S4, S2) were found on the surface of rice husks and kaolin clay type (L3, L4) in stomach and intestine
fluids, respectively. On Iraqi kaolin clay, adsorption is well described by the pseudo-second-order model, and the Tempkin adsorption isotherm
provides a good fit for the Stomach. Whereas adsorption on rice husk is well described by the Freundlich isotherm, which is a good fit for the
intestine. the adsorption is predominantly physical. The best maximum adsorption capacities were calculated on both surfaces in the following
order: stomach-kaolin>intestinal fluids-rice husks>stomach-rice husks>intestinal fluids-kaolin.
Conclusion: Both kaolin and rice husk are possible adsorbents that could be used to get antibiotics out of water.