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Background: Acinetobacter baumannii is the cause of opportunistic nosocomial infection and one of the six major multidrug-resistant bacteria in hospitals worldwide. Objectives: Blood stream infections and ventilator-associated pneumonia are the most…
Background: Acinetobacter baumannii is the cause of opportunistic nosocomial infection and one of the six major multidrug-resistant bacteria in hospitals worldwide. Objectives: Blood stream infections and ventilator-associated pneumonia are the most frequent diseases brought on by this human bacteria, and mortality can reach 35%. Methodology: In this study, 77 blood and urine samples were collected from children who had been receiving treatment for Acinetobacter infection at AL-Zahra teaching hospital in Al-Najaf, Iraq, for two years. In contrast to the 24 Acinetobacter spp. recovered in 2021–2022, only 53 Acinetobacter spp. were found in 2020–2021. Results: The findings showed that Acinetobacter isolates were divided into the following species: In 2020–2021, Acinetobacter spp. cause 9.43% of the isolates, 1.8% of the isolates were Acinetobacter lwoffii, and 88.6% of the population was Acinetobacter baumannii. The isolates of Acinetobacter spp. that were used in this study were resistant to a variety of antibiotics, including CIP (73.3%), CAZ (89.13%), MEM (68.2%), CTX (89.4%), IPM (83.3%), LEV (75%), TOB (62.5%), and SXT (70.27%). This is in contrast to the isolates that were collected in 2020–2021, which had higher resistance percentages toCIP(57. 8%), CAZ (83.3%), MEM (45.45%), CTX (90.90%), IPM (44.44%), LEV (41.6%), TOB (20%), SXT (55.5%) for isolates that collected in 2021-2022. Conclusions Acinetobacter baumanni isolates from blood and urine. have been recognized as an important pathogen that causes various infection in Najaf City. High antibacterial agent’s resistance among Acinetobacter spp. and MAR index was a concern among these isolates. There are increasing in the antibiotic resistance of Acinetobacter spp for COL, TOD, TIG and POLB in 2021-2022 period
INTRODUCTION
Acinetobacter bacteria is a pleomorphic aerobic gram-negative bacillus commonly isolated from the hospital environment and hospitalized patients. The Acinetobacter has more than 50 species, most of which are nonpathogenic environmental organisms. The most common infection-causing species is Acinetobacter baumannii, Acinetobacter calcoaceticus and Acinetobacter lwoffii 1. This type of Acinetobacter can cause a variety of infections in people, including: blood infections (fever, Chills, vomiting, confusion), urinary tract infections (frequency, urgency, dysuria, hematuria, cloudy urine, foul smelling urine), pneumonia and wound infection2. Healthcare facilities all over the world struggle with A. baumannii's in famous tendency to create and gain resistance to almost every antibiotic in our arsenal3. However, the most hazardous conditions that A. baumannii can cause include bacteremia and ventilator-associated pneumonia (V
