Assessment of Antibiotic Sensitivity of Pseudomonas aeruginosa Isolated from Different Clinical Samples
الباحث الأول:
Al-Makhzoomy, Taghreed Abdul Kareem
الباحثين الآخرين:
Mahdi Al-Challabi, Khamael A.Obaid Khzal, Alaa M.
المجلة:
Egyptian Journal of Medical Microbiology (Egypt)
تاريخ النشر:
1 يناير، 2025
مختصر البحث:
Abstract
Background: One of the most significant threats to global public health and development is antimicrobial resistance (AMR). Pseudomonas aeruginosa (P. aeruginosa) is directly associated with the issue of AMR and is a major cause of both chr…
Abstract
Background: One of the most significant threats to global public health and development is antimicrobial resistance (AMR). Pseudomonas aeruginosa (P. aeruginosa) is directly associated with the issue of AMR and is a major cause of both chronic lifelong diseases and life-threatening acute infections. In Iraq, the rising prevalence of carbapenem-resistant P. aeruginosa poses a substantial threat to public health. Objectives: This study aimed to compare and evaluate the results of drug sensitivity testing for P. aeruginosa isolates from different clinical samples. Methodology: Different samples were collected from clinical cases attending Al-Sadder Medical City Hospital, Iraq, these were wounds, otitis media, urinary tract infections (UTIs) and vaginitis. P. aeruginosa was isolated and identified by the routine bacteriological methods and validated by using the VITEK® 2 system. The antibiotic sensitivity of the isolates was determined by AST techniques. Result: One hundred P. aeruginosa strains were identified. The results indicated that the majority of P. aeruginosa showed high resistance to Amoxicillin + Clavulanic acid (AMC), In contrast, there was significantly less resistance to (IPM) Imipenem. Conclusion: Imipenem (IPM) and (MEM) Meropenem were the promising antimicrobial agents used to treat the P. aeruginosa infections. © 2025, Egyptian Society for Medical Microbiology (ESMM). All rights reserved.
