NEW OXIDATIVE COUPLING REACTION FOR SPECTROPHOTOMETRIC DETERMINATION OF 2-ISOPROPYL-5- METHYL PHENOL
الباحث الأول:
Lamia Abdultef Rissn
الباحثين الآخرين:
Riyadh Radhi Mohammed, Mustafa Abdulkadhim Hussein
المجلة:
WORLD JOURNAL OF PHARMACEUTICAL RESEARCH ,
Impact Factor : 8.084
ICV : 90.8
تاريخ النشر:
None
مختصر البحث:
Abstract
A superficial spectrophotometric method for determination of microgram amounts of 2-isopropyl-5-methyl phenol in pure mouthwash. The technique is based on an oxidative coupling reaction between 2-isopropyl-5-methyl phenol(thymol) and 2,5 d…
Abstract
A superficial spectrophotometric method for determination of microgram amounts of 2-isopropyl-5-methyl phenol in pure mouthwash. The technique is based on an oxidative coupling reaction between 2-isopropyl-5-methyl phenol(thymol) and 2,5 di methoxy aniline in the basic medium which shows maximum absorption at 452nm. Beer’s law has obeyed the range of (2-40) μg.ml-1 of thymol. A molar absorptivity (1.6997×104) l mol-1 cm-1, and Sandell index of 0.013μg/cm2. The best conditions for all color development are described and proposed methods were successfully applied to the determination of thymol in mouthwash arrangements. The communal excipients and extracts did not affect in this method.