مختصر البحث:
Multiple resistances to antimicrobial drugs arising in Escherichia coli isolates may complicate therapeutic
management of urinary tract infection (UTI) by this organism. In order to assess the multidrug resistance
(MDR) among urinary E. coli isola…
Multiple resistances to antimicrobial drugs arising in Escherichia coli isolates may complicate therapeutic
management of urinary tract infection (UTI) by this organism. In order to assess the multidrug resistance
(MDR) among urinary E. coli isolates, we have tested 27 antimicrobial drugs against 192 isolates from
patients with significant bacteriurea from 3 hospitals in Najaf during june to Augest 2011. The number of
patients with urinary tracts infection was higher in females, 136 (70.9%) compared to males, 56 (29.1%).
The antibiotic susceptibility patterns of isolates were determined by disk diffusion method. Among the
isolates from the hospital patients, 95.3%, 94.3%, 93,8%, 92.2%, 91.7%, and 90.1% were resistant to
carpencillin, ticarcillin, ampicillin, cefepim, cefamandol, and pipracillin, respectively; Resistant profile for
cefoxitin, and amoxicillin was 85.4% and 80.2%, respectively. Uoropathogenic E. coli was resistant to
cefotaxime, cefetriaxon, and Aztreonam (71.4%), and resistance to trimetheoprim, doxicycllin, ceftazidim,
amoxiclave, and nalidixic acid were 69.8%, 68.2%, 68.8%, 67.2%, and 61%, respectively. susceptibility
prfile to aminoglycosid antibiotics (tobramycin, gentamycin, and amikacin) were 56.8%, 53.1%, and
10.4%, respectively. And for fluoroquinolons (ciprofloxacin, norfloxacin, ofloxacin, and levofloxacin) were
49%, but for gatifloxacin, resistant was 40.6%. E. coli was resistance to chloramphenicol and nitroforantoin
17.7% and 12%, respectively.The high prevalence of drug resistance among UTI patients calls for
continuous surveillance to assure effective control of this infection.
