The effect of birth asphyxia on the coagulation status in neonates
الباحث الأول:
Dr. Rajaajabbarkadhum ,MBChB,DCH,CABP
الباحثين الآخرين:
Dr.Hithabjawadmuhsen , MBChB,DCH,CABP
Dr.ashwaq ali hussein
المجلة:
karbala medical journal
تاريخ النشر:
None
مختصر البحث:
Abstract
Background : birth asphyxia has multi system effect .
Objective: To study the effects of birth asphyxia & perinatal events on the coagulation status of newborn infants.
Methods: Across sectional study was done on 27 neonates with birth…
Abstract
Background : birth asphyxia has multi system effect .
Objective: To study the effects of birth asphyxia & perinatal events on the coagulation status of newborn infants.
Methods: Across sectional study was done on 27 neonates with birth asphyxia in AL-Zahraa teaching hospital in Najaf city from period of first of march 2011 to June 2011. Blood samples were collected from the neonates within the first 24 hrs. after birth and sent for investigations including PT, PTT, serum fibrinogen and platelet count.
Results: The study showed statistically significant effect of birth asphyxia on platelet count especially in severely asphyxiated neonates 0 – 3 at 5 min. after birth (plat. Count > 100,000 per mm3) in comparison to neonates with Apgar score of 4 – 6 at 5min, after birth. Infants who have very low birth wt. ( i.e>1500 gms) had significantly lower platelet count (> 100,000 per mm3) than infants with birth wt.<1500 gms.
Birth asphyxia had no significant effect on PT, PTT, or fibrinogen level. Other perinatal and prenatal variables examined as (sex, maternal hypertension, DM, mode of delivery gestational age) did not show any significant association with coagulation status which may be explained by the small number of infants studied.
Conclusion: Thrombocytopenia (plat. >100.000 per mm3) is seen in neonates with Apger score ( 0-3) at 5 min. and in neonates with very low birth wt. (>1500gms). No statistically significant relation between birth asphyxia and PT, PTT and serum fibrinogen level.
