Square-wave voltammetric technique determination of testosterone in pure form and pharmaceutical applications
الباحث الأول:
Hayder Yaseen Noor Aljaberi
الباحثين الآخرين:
Muthana S. Mashkour
المجلة:
JOURNAL OF KUFA FOR CHEMICAL SCIENCES
تاريخ النشر:
18 فبراير، 2026
مختصر البحث:
abstract:%0AThis%20study%20uses%20a%20glassy%20carbon%20electrode%20(GCE)%20and%20the%20square-wave%20voltammetric%20(SWV)%20method%20to%20measure%20testosterone.%20Testosterone%20(TST)%20was%20found%20in%20pharmaceutical%20formulations%20using%20th…
abstract:%0AThis%20study%20uses%20a%20glassy%20carbon%20electrode%20(GCE)%20and%20the%20square-wave%20voltammetric%20(SWV)%20method%20to%20measure%20testosterone.%20Testosterone%20(TST)%20was%20found%20in%20pharmaceutical%20formulations%20using%20the%20SWV%20approach,%20which%20is%20renowned%20for%20its%20great%20sensitivity%20and%20selectivity.%20Over%20a%20concentration%20range%20of(3.467%20%C3%97%2010-5%20-%203.467%20%C3%97%20104)%20form%20M,%20the%20approach%20demonstrated%20a%20linear%20response%20with%20(%20LOD)%20of%206.22%C3%9710-?%20M%20and%20(LOQ)%20of%201.884%C3%9710-6%20M.%20It%20also%20had%20remarkable%20repeatability%20(RSD%20%3C%205%25).%20Selective%20detection%20was%20achieved%20through%20careful%20pH%20adjustment%20and%20electrode%20modification,%20mitigating%20matrix%20interferences.%20Validation%20via%20recovery%20studies%20in%0Acommercial%20samples%20yielded%2097-101%25%20accuracy,%20underscoring%20the%20method's%20reliability.%20According%20to%20the%20scan%20rate%20analysis,%20the%20process%20is%20totally%20irreversible%20in%20the(0.02-0.5)%20V/s%20range,%20and%20diffusion%20and%20adsorption%20control%20the%20oxidation%20of%20TST%20on%20the%20GCE%20surface.%20(TST)%20showed%20an%20irreversible%20oxidation%20peak%20of%20around%20+1.490%20V%20GCE.%20The%20method's%20effective%20application%20in%20the%20analysis%20of%20testosterone%20in%20pure%20form%20and%20pharmaceutical%20formulations%20further%20confirms%20its%20applicability%20and%20confirms%20its%20potential%20for%20use%20in%20clinical%20monitoring,%20pharmacokinetic%20investigations,%20and%20quality%20control.
