Synthesis and Characterization of New 1, 3, 4-
Thiadiazoles Substituted with Imidazolidine Moiety
الباحث الأول:
FaezAbdul-Hussien Alrammahi1,
الباحثين الآخرين:
Qasim Mehdi Ismael1,Zeid Hassan Abood3
المجلة:
International Journal of Science and Research (IJSR)
تاريخ النشر:
None
مختصر البحث:
Abstract: 2-amino-5-mercapto-1,3,4-thiadiazolewas introduced in condensation reactions with both terephthaldehyde and 4-
dimethylaminobenzaldehyde to yield imine derivatives1a and 1b respectively. The resulting imine1awas treated with amino acids L…
Abstract: 2-amino-5-mercapto-1,3,4-thiadiazolewas introduced in condensation reactions with both terephthaldehyde and 4-
dimethylaminobenzaldehyde to yield imine derivatives1a and 1b respectively. The resulting imine1awas treated with amino acids L-
valine and L-cysteine, also the imine 1b wasreacted with amino acids L-cysteine, L-isoleucine and L-tyrosine to obtain five new
imidazolidine derivatives2a-erespectively.2-amino-5-mercapto-1,3,4-thiadiazolewas also converted to the corresponding azoaldehyde derivative3 through coupling reaction of its diazonium salt with 4-hydroxybenzaldehyde dissolved in sodium hydroxide solution. The resulting azoaldehyde 3 was reacted with2-amino-5-mercapto-1,3,4-thiadiazoleto give the corresponding azoimine derivative 4. Treatment of the resulting azoimine 4 with amino acids glycine, L-valine and L-cysteine afforded three new imidazolidine derivatives5a-
crespectively.