Estimation of plasma TGF-β1 after intra-articular platelet rich plasma injection in-patient with anterior disc displacement with intermittent locking of TMJ disorder
الباحث الأول:
Issa Hasan Issa
الباحثين الآخرين:
Muhassad H. Al-Mudhafar, Karar Abdulzahra Mahdi
, Ali A. AlFahham
المجلة:
latin american jornal of farmacy
تاريخ النشر:
None
مختصر البحث:
Abstract
Background: Temporomandibular Disorder (TMD) describes a set of musculoskeletal troubles in the masticatory system and is the major cause of non-dental originated pain in the oro-facial area which includes the head, face and associated st…
Abstract
Background: Temporomandibular Disorder (TMD) describes a set of musculoskeletal troubles in the masticatory system and is the major cause of non-dental originated pain in the oro-facial area which includes the head, face and associated structures. The etiology of TMD has not been yet determined by occlusion, temporomandibular joint (TMJ) anatomy, functional and psychological factors can be concerned. Internal derangement of the TMJ is one of the most common types of TMD, referring to an unusual position of the articular disk in relation with the mandibular condyle and the articular eminence of the temporal bone. The main goal of the treatment for TMJID is to raise the range of motion and decrease the functional pain of the TMJ. Intra-articular administration of medications is a well-known management method in orthopedic and rheumatic disorders related to pain, effusion, inflammation of cartilage, bone and joint capsules and fibrous adhesions. The aim of the present study was to investigate the plasma levels of TGF-β1 before and after PRP injection, to evaluate the clinical improvement of mandibular function and pain intensity.