New hydrophilic grafting cellulose based on amino-carboxylic acid: Synthesis and antibacterial evaluation
الباحث الأول:
Hayder M. Kamal
الباحثين الآخرين:
Asaad H. Aneed
, Dhurgham Aziz
, Nuha S. Kareem
, Maryam M.
Mahdi
, Zahraa H. Hamid
المجلة:
Journal of Bioscience and Applied Research
تاريخ النشر:
25 مارس، 2025
مختصر البحث:
ABSTRACT
Background: There is a growing interest in developing the antibacterial properties of hydrophilic polymers.
Methods: In this research, new grafting cellulose based on amino-carboxylic acids are obtained, and their
biological activities a…
ABSTRACT
Background: There is a growing interest in developing the antibacterial properties of hydrophilic polymers.
Methods: In this research, new grafting cellulose based on amino-carboxylic acids are obtained, and their
biological activities are evaluated. The sequences are started by treating cellulose with tosylate chloride to get
2, which further reacts with sodium azide. Results: To produce compound 3. Azide reduction to amino analog
by sodium sulfide produces compound 4. The alkylation with chloroacetic acid compound 5 is obtained with
amino-acid residue 5. Conclusions: Finally, extensive antibacterial studies have been performed against two
types, Staphylococcus aureus and Escherichia coli. The results demonstrated that the novel derivatives may
influence bacteria at low concentrations, and their water solubility could lead to them being biocompatible
agents.
