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Gender-related response to different wavelength low-level laser therapy in orthodontic mandibular canine movement: a split mouth study

الباحث الأول: Almustafa Alhumadi

المجلة: Endodontics today

تاريخ النشر: 6 يناير، 2026

مختصر البحث:

INTRODUCTION. Low-level laser therapy (LLLT), known as photobiomodulation (PBM), has recently attracted the attention of clinicians to speed up orthodontic tooth movement. Nevertheless, the sex-related effects of LLLT have not been investigated ye… INTRODUCTION. Low-level laser therapy (LLLT), known as photobiomodulation (PBM), has recently attracted the attention of clinicians to speed up orthodontic tooth movement. Nevertheless, the sex-related effects of LLLT have not been investigated yet, although the role of sex hormones on bone remodeling has already been reported. The objective of this study was to determine if LLLT preferentially accelerates the rate of mandibular canine retraction in men or women. MATERIALS AND METHODS. Twenty systemically healthy patients (10 male, 10 females; age range from 18 to 25 years) who were undergoing fixed orthodontic treatment were included in a split-mouth randomized con- trol trial. Subjects were stratified into two groups: Group 1 (n = 10) was treated with 650 nm LLLT on the ex- perimental side, while group 2 (n = 10) was treated with 976 nm LLLT. Opposite sides of the animals were used as a sham-irradiated control. PBM parameters were compatible (8 J/cm2 energy density, 0.26 W/cm2 power density) and administered on d 0, 3, 7, 14, then bi-weekly thereafter. Retraction of canine was done with 150 g force produced by elastics. Amount of linear tooth movement was evaluated at 1 month and space closure duration was monitored until complete closure. RESULTS. The amount of the canine movement was significantly higher on LLLT treated sides compared to control ones after 1 month (p < 0.001, mean difference: 0.92 ± 0.46 mm; 1.44 ± 0.29 mm vs control sides, re- spectively). Better acceleration was obtained at 976 nm (1.12 ± 0.44 mm gain) vs. 650 nm (0.71 ± 0.39 mm; p < 0.001). LLLT sides closed spaces in 3.3 months, whereas controls took 6.2 months for complete closure. Sex stratification found that the accelerations were consistently higher in waves for both males and females indicating no sex-by-wavelength interactions. CONCLUSIONS. LLLT efficiently speeds up the retraction of the mandibular canine, and the 976 nm wave- length works best. Sex does not affect the effectiveness of LLLT, which supports the consistent use of similar procedures across different groups of patients. Keywords: photobiomodulation, orthodontic tooth movement, canine retraction, sex differences, laser therapy, near-infrared

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Determination of Minimum Inhibitory Concentration and Minimum Bactericidal Concentration of Zinc Oxide Nanoparticles from Internal Cavity of Dental Implant and Natural Teeth (in vitro study)

الباحث الأول: Dhyaa M. J. Hirz AL-Deen 1

الباحثين الآخرين: , Marwah Safaa Ali 2, Almustafa Alhumadi 3*

المجلة: Journal of nanostructures

تاريخ النشر: 1 أكتوبر، 2025

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Nanotechnology characterizes a new knowledge that potentials to deliver a wide range of uses and improved technologies for biological and biomedical applications. Nanotechnology permits synthesis of materials that have structure is less than 100 …

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Investigation of bioactivity, biocompatibility, and antibacterial properties of a hydroxyapatite- enhanced nanocomposite for dental applications

الباحث الأول: Xin Yan

الباحثين الآخرين: 1,16, Ali ebrahimi2, Reza Mohammadi3, Mona Mohajeri Tehrani4, Pardis Chaboki5 , Mohammed Mustafa6, Almustafa Alhumadi7,8,9, I. B. Sapaev10,11,12, Ahmed Hjazi13 , Khadije Yousefi14 & Mojdeh Yousefi15

المجلة: Scientific Reports

تاريخ النشر: 5 أغسطس، 2025

مختصر البحث:

The prolonged setting duration of mineral trioxide aggregate (MTA) constitutes one of its principal limitations. In contrast, Nano Fast Cement (NFC) emerges as an innovative nanocomposite characterized by a rapid setting time. To develop an outsta…

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Gender differences in lower facial soft tissue thickness among different skeletal patterns, based on soft tissue cephalometric analysis

الباحث الأول: Almustafa Alhumadi

الباحثين الآخرين: Thaer Jaber Al-Khafaji , Ali Mihsen Hussein Alyassiri , Wisam W Alhamadi

المجلة: Wolters Kluwer - Medknow

تاريخ النشر: 13 أكتوبر، 2022

مختصر البحث:

Abstract Objective: Lower face soft tissue thickness and dentoskeletal features form the lower facial profile. Sagittal skeletal malocclusions with varying degrees of soft tissue thickness in males and females were herein examined using soft tissue…

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An assessment of mineral concentration of dental enamel neighbouring hypothetical orthodontic brackets using X-ray microtomography

الباحث الأول: Thaer Jaber Al-Khafaji

الباحثين الآخرين: Thaer Jaber Al-Khafaji , Bahn Agha , Almustafa Alhumadi , Wisam W. Alhamadi , David Mills , Graham Roy Davis , Alexander J. Cresswell-Boyes , Padhraig S. Fleming

المجلة: Elsevier B.V.

تاريخ النشر: 23 سبتمبر، 2022

مختصر البحث:

Abstract Objectives Differences in the mineral concentration (MC) level of dental enamel may represent a precursor of white spot lesions adjacent to fixed orthodontic brackets. The aim of the current in vitro study was to compare the MC level cent…

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Management of a large venous malformation of the lower lip using dual-wavelength (810 nm and 980 nm) diode laser photocoagulation therapy: a case report

الباحث الأول: Hani M. Al-Kufi

الباحثين الآخرين: Hani M. Al-Kufi, Abbas A. Y. Taher, Dhyaa M. J. Hirz Al-Deen & Almustafa Alhumadi

المجلة: springer nature

تاريخ النشر: 22 أكتوبر، 2024

مختصر البحث:

Abstract Purpose The aim of this study is to evaluate the effectiveness and safety of dual-wavelength (810 and 980 nm) diode laser photocoagulation therapy in the management of venous malformations. Materials and methods A 49-year-old female p… Abstract Purpose The aim of this study is to evaluate the effectiveness and safety of dual-wavelength (810 and 980 nm) diode laser photocoagulation therapy in the management of venous malformations. Materials and methods A 49-year-old female patient was referred to the Department of Laser at Naser Al-Mousawi Specialized Dental Center, complaining of a large, painless mass on her lower lip. The lesion was asymptomatic and covered a large portion of the lower lip. According to the patient, the lesion had been present since birth. Additionally, the size of the lesion had increased over the past 20 years. Upon clinical examination, the mass appeared dark purplish in color, soft, and compressible, indicating a low-flow vascular malformation. The patient was referred for a Color Doppler Ultrasound to evaluate the type and flow rate of the lesion. The results revealed characteristic features of a low-flow malformation (low flow and lack of pulsatility). The treatment was performed by photocoagulation using the QuickLase dual-wavelength (810–980 nm) diode laser. The laser parameters included a total power of 1.2 W, divided equally between the two wavelengths: 0.6 W from the 810 nm wavelength and 0.6 W from the 980 nm wavelength. The mode of operation was pulsed emission (100 ms pulse duration), and the diameter of the fiber optic tip was 400 μm. The fiber optic tip was not initiated and was positioned as close as possible to the lesion, without making contact. The treatment was done in two sessions, with the second session performed one month after the initial treatment to eliminate the entire lesion, followed by three-month and six-month follow-up periods. Results The results obtained from the study showed significant improvement. The initial swelling and discoloration resolved almost completely, and the tissue returned to a near-normal state with no residual effects or signs of recurrence observed during the three-month and six-month follow-up periods following laser photocoagulation therapy. Conclusions According to the study results, photocoagulation therapy using a diode laser is considered an effective method for managing vascular lesions due to its simplicity, high patient acceptance, minimal invasiveness, excellent healing, and fewer postoperative complications. Imaging, particularly color Doppler ultrasound, is crucial in diagnosing large vascular malformations, as it can identify flow patterns and determine the extent of the lesion. Regarding the number of treatment sessions, in cases of large vascular lesions, a single session may be insufficient to completely eliminate the lesion, often necessitating multiple sessions.

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Almustafa Alhumadi [PDF] from researchsquare.com Therapeutic and analgesic efficacy of Photobiomodulation Therapy (PBMT) in the management of trigeminal neuralgia: a case report

الباحث الأول: Hani M. Al-Kufi

الباحثين الآخرين: Hani M. Al-Kufi, Almustafa Alhumadi, Marwah S. Ali & Dhyaa M.J. Hirz Al-Deen

المجلة: springernature

تاريخ النشر: 19 نوفمبر، 2024

مختصر البحث:

Abstract Purpose The aim of this study is to evaluate the therapeutic and analgesic effect of PBMT in management of trigeminal neuralgia. Methods A 42-year-old female patient was chosen for this study. She experienced severe, unilateral, elect…

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A comparative evaluation of postoperative re-pigmentation following gingival depigmentation using a 940-nm diode laser and abrasion method: “method: a split-mouth study”

الباحث الأول: Hani M. Al-Kufi

الباحثين الآخرين: Hani M. Al-Kufi, Almustafa Alhumadi & Shiamaa M. Huthiafa

المجلة: springer nature

تاريخ النشر: 13 ديسمبر، 2023

مختصر البحث:

Abstract Purpose The aim of this study is to evaluate the re-pigmentation following gingival depigmentation procedure using a diode laser and abrasion method. Methods A group of 20 patients (comprising 4 males and 16 females), aged between 12 … Abstract Purpose The aim of this study is to evaluate the re-pigmentation following gingival depigmentation procedure using a diode laser and abrasion method. Methods A group of 20 patients (comprising 4 males and 16 females), aged between 12 and 37 years old, were selected for the study. Inclusion criteria involved patients exhibiting moderate to severe gingival hyperpigmentation on both the left and right sides of the anterior maxillae. Exclusion criteria included pregnancy and lactation, gingival hyperpigmentation associated with systemic conditions or lesions, patients with medical conditions, smokers, and patients under medication associated with hyperpigmentation. The study was designed as a split-mouth study, wherein the upper left anterior sextant of all subjects (from the first central incisor to the second premolar) was treated by abrasion method. Simultaneously, the upper right sextant (from the first central incisor to the second premolar) for the same patient was treated using a 940-nm diode laser. The laser settings comprised a power of 1.2 W and a pulse emission mode with an initiated tip (400 μm) placed in contact with the tissues. Both depigmentation techniques were performed on the same day by a single operator. Results The results indicate a highly significant difference in the mean pigmentation index before treatment and after a 10-month period (p-value = 0.000). No statistically significant differences were observed in the mean pigmentation index between the laser and abrasion methods over the 10-month post-surgery duration. As for the association between patient complexion and re-pigmentation, 7 out of 16 patients with a brown complexion exhibited re-pigmentation, while no re-pigmentation was observed among patients with a fair complexion after a period of 10 months post-surgery. This indicates the presence of a direct relationship between patient complexion and re-pigmentation. Conclusions Based on the study’s findings, both depigmentation methods were effective, with the laser technique notably safer and easier to perform compared to abrasion method. Interestingly, re-pigmentation could occur irrespective of the method used, indicating that individuals with brown or dark complexions had a higher likelihood of re-pigmentation compared to fair-skinned individuals. Considering these results, individuals genetically predisposed to gingival pigmentation should be informed about the potential for recurrence before the procedure, as sustained outcomes might not be guaranteed.

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EFFECT OF RESIN INFILTRANT PRETREATMENT ON SHEAR BOND STRENGTH OF METAL ORTHODONTIC BRACKETS IN VITRO STUDY

الباحث الأول: Wisam W. Alhamadi

الباحثين الآخرين: Wisam W. Alhamadi, Essam Osman , Fayez Saleh Ahmed M. AL-Mayali , Almustafa Alhumadi, Zainab Alrufaye,

المجلة: biocore publishing group

تاريخ النشر: 30 يوليو، 2018

مختصر البحث:

Abstract Background: The primary purpose of this study is to determine the effect of Caries resin Infiltrant (Icon) on the shear bond strength of metal orthodontic brackets using three adhesive systems. Materials and methods: Sixty-six extracte…

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Relationship between Maxillary Occlusal Plane Inclination and Soft Tissue Harmony in Adults with Different Sagittal Skeletal Malocclusions

الباحث الأول: Almustafa Alhumadi

الباحثين الآخرين: Almustafa Alhumadi , Essam Osman, Joseph Bouserhal

المجلة: biocorepublishinggroup

تاريخ النشر: 28 مايو، 2021

مختصر البحث:

A harmonious soft tissue profile, as an important treatment goal in orthodontics, is sometimes difficult to achieve, partly because the soft tissue overlying the teeth and bones is highly variable in its thickness. These variations result not o… A harmonious soft tissue profile, as an important treatment goal in orthodontics, is sometimes difficult to achieve, partly because the soft tissue overlying the teeth and bones is highly variable in its thickness. These variations result not only from imbalance of the dental and skeletal structures but from individual variations in the thickness and tension of the soft tissues. Objective: To investigate the relationship between maxillary occlusal plane inclination and soft tissue harmony of the face in different sagittal skeletal malocclusions. Material and Methods: The study was a cross-sectional observational study. Lateral cephalometric x-rays of 160 individuals were collected from the Orthodontic clinic at the Faculty of Dentistry, Beirut Arab University and divided into 4 equal groups based on ANB as a parameter of intermaxillary skeletal relationship: Class I (CI) (0≤ ANB ≤4), Class II division 1 (CII div 1) (ANB > 4 with normal or proclined upper incisors), Class II div 2 (CII div 2) (ANB > 4 with retroclined upper incisors) and Class III (CIII) (ANB < 0). Hard tissue analysis included 1 angular measurement for maxillary occlusal plane (MxOP) inclination. Soft tissue analysis included 2 angular measurements for facial convexity and 3 linear measurements for inter-jaw harmony and 7 linear measurements for soft tissue thickness. Results: There was significant correlation between MxOP angle and facial contour angle, as well a Sn-Pog’ for participants with CI. In CII div 1, there was a significant correlation between MxOP angl and ULA-LLA, as well as chin thickness V. In CII div 2, there was a significant correlation between MxO angle and Sn-Pog’, ULA-LLA, upper lip strain, chin thickness H, and chin thickness V. In class III, there was no significant correlation Conclusion: H angle, facial contour angle, inter-jaw harmony and soft tissue thickness parameters were not always correlated with MxOP angle and this correlation was highly variable between different skeletal malocclusions. Therefore one cannot fully support the existence of a relation between MxOP and soft tissue harmony.

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Orthosurgical Correction of Unilateral Condylar Hyperplasia and Severe Facial Asymmetry: Case Series Study

الباحث الأول: Fayez Saleh

الباحثين الآخرين: Fayez Saleh Wisam W. Alhamadi Almustafa Alhumadi

المجلة: BP International

تاريخ النشر: 31 مايو، 2021

مختصر البحث:

ABSTRACT Purpose: The purpose of the present study was to emphasize the importance of thorough case analysis including all possible diagnostic measures of facial asymmetry prior to formulating an appropriate treatment planning and select the rele…

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Orthosurgical Management of Median Cleft Lip and Palate, A Multidisciplinary Approach: Case Report

الباحث الأول: Wisam Al Hamadi

الباحثين الآخرين: Wisam Al Hamadi, F. Saleh, Mohamad Kaddouha, Almustafa Alhumadi

المجلة: EC DENTAL SCIENCE ecronicon

تاريخ النشر: 7 فبراير، 2018

مختصر البحث:

Objective: To present a new standard of care for a complex rare median maxillary cleft and emphasize on the principles that such cases are best treated by interdisciplinary team of specialists with experience in this field. Materials and Methods: … Objective: To present a new standard of care for a complex rare median maxillary cleft and emphasize on the principles that such cases are best treated by interdisciplinary team of specialists with experience in this field. Materials and Methods: A female patient aged 9 years 6 months presented with a median cleft of lip and palate (premaxilla with four anterior teeth were lost), surgical repair was performed at an early age with visible scar. Full clinical and radiographic records were collected and initially analyzed jointly by an orthodontist, implantologist and maxillofacial surgeon. The maxilla exhibited a deficiency in three planes of space. There was an anterior and posterior cross bite with distorted occlusal plane and anterior open bite. Due to loss of basal support, the nose was severely depressed with flat alar bases (loss of nasal cartilaginous support). The clinicians agreed upon a long-term treatment planning started with orthopedic intervention, orthodontic presurgical preparation, alveolar bone grafting, maxillofacial surgery, nasal reconstruction, postsurgical orthodontic care, placement of dental implants, and prosthetic phase. Results: A significant improvement in facial contour was realized. Lower anterior facial height was reduced by 8.3 mm (angular 11.3°); lips became competent at rest and teeth-to-lip relationship created a beautiful smile, alar bases favorably widened improving nasal esthetics. Conclusions: Despite patient and parents’ satisfaction with the outcome, the long duration of treatment (almost 13 years) for a school-aged girl, and the shuttle movement from private practice to another then to hospital were a burden on the family. This calls for establishing medical centers in Lebanon with a well-trained independent craniofacial professional team, in which all members are involved in conducting a joint evaluation (face-to-face group meeting) and negotiate a comprehensive treatment plan. Keywords: Median Cleft Lip and Palate; Multidisciplinary Approach; Maxillofacial Surgery; Postsurgical Orthodontic Care; Prosthetic

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Inhibitors of Academic Progress in Arab Universities

الباحث الأول: Fayez Saleh

الباحثين الآخرين: Fayez Saleh1, Wisam W. Alhamadi2, Almustafa Alhumadi3

المجلة: International Journal of Dentistry and Oral Health

تاريخ النشر: 26 فبراير، 2021

مختصر البحث:

Backgrounds: The purpose of this review is to create awareness among educational policymakers that poor global ranking of our higher education institutions necessitates an in-depth search for the possible constraints that hinder their academic pro…

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المصطفى وسام وهاب الحمادي

المصطفى وسام وهاب الحمادي

الملف الشخصي

الاهتمامات البحثية

البحوث المنشورة

Gender-related response to different wavelength low-level laser therapy in orthodontic mandibular canine movement: a split mouth study

Determination of Minimum Inhibitory Concentration and Minimum Bactericidal Concentration of Zinc Oxide Nanoparticles from Internal Cavity of Dental Implant and Natural Teeth (in vitro study)

Investigation of bioactivity, biocompatibility, and antibacterial properties of a hydroxyapatite- enhanced nanocomposite for dental applications

Gender differences in lower facial soft tissue thickness among different skeletal patterns, based on soft tissue cephalometric analysis

An assessment of mineral concentration of dental enamel neighbouring hypothetical orthodontic brackets using X-ray microtomography

Management of a large venous malformation of the lower lip using dual-wavelength (810 nm and 980 nm) diode laser photocoagulation therapy: a case report

Almustafa Alhumadi [PDF] from researchsquare.com Therapeutic and analgesic efficacy of Photobiomodulation Therapy (PBMT) in the management of trigeminal neuralgia: a case report

A comparative evaluation of postoperative re-pigmentation following gingival depigmentation using a 940-nm diode laser and abrasion method: “method: a split-mouth study”

EFFECT OF RESIN INFILTRANT PRETREATMENT ON SHEAR BOND STRENGTH OF METAL ORTHODONTIC BRACKETS IN VITRO STUDY

Relationship between Maxillary Occlusal Plane Inclination and Soft Tissue Harmony in Adults with Different Sagittal Skeletal Malocclusions

Orthosurgical Correction of Unilateral Condylar Hyperplasia and Severe Facial Asymmetry: Case Series Study

Orthosurgical Management of Median Cleft Lip and Palate, A Multidisciplinary Approach: Case Report

Inhibitors of Academic Progress in Arab Universities

المحاضرات

orthodontic tooth movement تقويم الاسنان

removable orthodontic appliance تقويم الاسنان

extraction in orthodontics تقويم الاسنان

orthodontic treatment planning تقويم الاسنان

diagnostic records in orthodontics تقويم الاسنان

buccal canine retractor تقويم الاسنان

recurved z spring تقويم الاسنان

treatment of crossbite تقويم الاسنان

treatment of class II Malocclusion تقويم الاسنان

treatment of class III malocclusion تقويم الاسنان