Characterization, Synthesis and Study of Biological Activity
of new Derivatives of Sulphadiazine
الباحث الأول:
1Ezat H. Zmam,
الباحثين الآخرين:
2Ahmed W. Radh, 3
Farked W. Salman
المجلة:
International Journal of ChemTech Research
تاريخ النشر:
None
مختصر البحث:
Abstract : Sulphadiazine converted to 2-chloro-N-(4-(N-pyrimidin-2-yl sulfamoyl) phenyl)
acetamide (A) as a result of reacation through chloroacetyl chloride is going to be responded
through sodium azide towards form 2-azido-N-(4-(N-pyrimidin-2-yl…
Abstract : Sulphadiazine converted to 2-chloro-N-(4-(N-pyrimidin-2-yl sulfamoyl) phenyl)
acetamide (A) as a result of reacation through chloroacetyl chloride is going to be responded
through sodium azide towards form 2-azido-N-(4-(N-pyrimidin-2-yl-sulfamoyl) phenyl
acetamide (B). 1,2,3-triazoline derivatives (S1-S7) were made through cycloaddition
responses among substance (B) which includes chalcones. Ready substances were being
stamped by T.L.C. , C.H.N.S. explanations, F.T.I.R spectra together with 1H-NMR range.
1,2,3-triazoline derivatives were checked for antibacterial activity.
Keywords : 1,2,3-triazoline, azide,anti bacterial activityandSulphadiazine
