مختصر البحث:
Otitis media is an acute upper respiratory tract infection-related inflammation of the middle ear and tympanic
membrane, frequently affecting children. Typically, a subsequent bacterial infection complicates a viral infection, which
ultimately cau…
Otitis media is an acute upper respiratory tract infection-related inflammation of the middle ear and tympanic
membrane, frequently affecting children. Typically, a subsequent bacterial infection complicates a viral infection, which
ultimately causes the condition. The study aims to study the function of bacterial ear infections and its causes, as well as
their resistance to medications, which was the focus of this investigation. The first axis of the research was the identification
of bacterial isolates using recognized diagnostic tools, and the second axis was determining the antibiotic's resistance and
sensitivity. Patients with otitis media were gathered from Al-Hakim General Hospital and Al-Sadr city hospital in Al-Najaf
city between November 2020 and April 2021 for 100 clinical samples. More than 80 samples were found to be infected
with bacteria. Bacterial strains found in this investigation are (30) isolates of Pseudomonas aeruginosa, (20) isolates of
Klebsiella spp, (20) isolates of Proteus spp, (15) isolates of Staphylococcus aureus, (8) isolates Escherichia coli and (7)
isolates Enterococcus fecalies. As part of this research, the disk diffusion method was used to assess how sensitive the
test was. The results showed that Pseudomonas aeruginosa was resistant to most antibiotics, particularly the penicillin
family, cephalosporin, and trimethoprim, with the existence of isolates resistant to meropenem. The investigation results
varied for the quinolone, aminoglycoside, and macrolide families. Klebsiella spp. were tested for antibiotic sensitivity
and found to be resistant to most antibiotics, particularly those in the penicillin family, cephalosporins, and trimethoprim.
Some quinolones, aminoglycosides, and macrolides are also resistant. Proteus spp were resistant to most antibiotics,
particularly the penicillin family (except for augmentin, which had some sensitive isolates) and cephalosporin (except for
cefdinir and cefepime) had some susceptible isolates) and trimethoprim, in addition to the presence of isolates resistant
to meropenem. There is a discrepancy in the examination results for the quinolone family. The aminoglycoside family
is also highly resistant. S. aureus isolates were resistant to penicillin (except for augmentin, which some isolates were
responsive to), trimethoprim, and quinolones, with the presence of isolates resistant to vancomycin. The macrolide class (
azithromycin) also has a significant resistance level. Escherichia coli is susceptible to meropenem, imipenem, and certain
cephalosporin generations. Augmentin, cefepime, cephalothin, meropenem, imipenem, and azithromycin were ineffective
against Enterococcus fecal. The conclusion is that Pseudomonas spp has a role in ear infections and the germs Klebsiella
spp., Proteus spp., Staphylococcus aureus, Escherichia coli, and Enterococcus fecalies. Penicillin and cephalosporin
resistance was seen in the majority of the identified isolates. The existence of isolates of Proteus and Pseudomonas
species resistant to meropenem. Vancomycin-resistant strains of Staphylococcus aureus isolates are present.
