Ionic liquid: A green designer solvent for topical delivery of Nano system
الباحث الأول:
Abulfadhel jaber neamah
الباحثين الآخرين:
Mowafaq M. Ghareeb
Department of Pharmaceutics, College of Pharmacy, Baghdad University, Baghdad, Iraq.
Asmaa M. Rashid
Department of Pharmaceutics, College of Pharmacy, Baghdad University, Baghdad, Iraq.
المجلة:
Maaen Journal for Medical Sciences
تاريخ النشر:
None
مختصر البحث:
Abstract
Ionic liquids (ILs) defined as organic salts that produced from combination of organic cation with various types of
organic/inorganic anions whose melting point less than 100 C. Because of their ionic character, most of ionic liquids
ex…
Abstract
Ionic liquids (ILs) defined as organic salts that produced from combination of organic cation with various types of
organic/inorganic anions whose melting point less than 100 C. Because of their ionic character, most of ionic liquids
exhibit useful properties such as no volatility, recyclability, good thermal stability, high conductivity and chemical
stability. Ionic liquid cationeanion combinations permits the solvents to be prepared such as N, N-dialkylimidazolium
as cation and acetate as anion. Ionic liquid was utilized as solvents or preparation components in various areas of drug
delivery systems, also as novel liquid forms of APIs in various stages of design drug delivery systems. Also their
incorporation with polymers has enabled the development of drug delivery systems for new therapeutic routes of
administration. Recently ionic liquid can be used as solubility and permeability enhancer to deliver drugs with poor
aqueous solubility and low lipophilicity by designing topical drug delivery of nano system.
