Association of pericardial fat volume with coronary
atherosclerotic disease assessed by CT angiography
الباحث الأول:
1H NAFAKHI, MD, FICMS
الباحثين الآخرين:
1H NAFAKHI, MD, FICMS, 1A AL-MOSAWI, MD, FICMS, 1H AL-NAFAKH, MD, FICMS and 2N TAWFEEQ, MD
المجلة:
bjr
تاريخ النشر:
None
مختصر البحث:
Objective: To investigate the association of pericardial fat volume (PFV) with coronary artery disease (CAD) in patients with intermediate pre-test probability of ischaemic heart disease assessed by coronary CT angiography. Methods: From a total of …
Objective: To investigate the association of pericardial fat volume (PFV) with coronary artery disease (CAD) in patients with intermediate pre-test probability of ischaemic heart disease assessed by coronary CT angiography. Methods: From a total of 115 consecutive Iraqi patients who underwent 64-multislice multidetector CT angiography examinations, only 74 patients (females, 38% and males, 68%) with a mean age of 5468 years were found to be eligible for statistical analysis. The patients were divided into two groups according to the median value of PFV (above and below 100ml). Results: The median value of PFV in our study was 100ml (range, 17–319ml). A significant association was observed between high PFV and significant coronary artery
stenosis (p50.005), between high PFV and significant left circumflex stenosis (p50.021) and between high PFV and the presence of coronary plaque (p50.005). Whereas there was no significant correlation between high PFV and coronary calcium score (p50.188), between high PFV and number of diseased coronary vessels (p.0.3), and between high PFV and body weight and body mass index. Conclusion: Increased PFV is strongly associated with the presence and severity of CAD. Advances in knowledge: Our study highlights the role of pericardial fat as an emerging biomarker in cardiovascular risk assessment and supports its association with the magnitude of CAD
