Study the Health indicators and liver enzymes changes in white rats
This study was conducted with the aim of reducing the toxic and negative effects of lead. Feeding rat’s different concentrations of medicinal plants (mint and parsley) powders are more efficient achieving the desired goal of the study. This process aims to produce an unconventional and widespread treatment for all people. A significant negative effect was observed on a group of variables through this study, such as the lead percentage in the blood increased from (4.5 µg / dl) to (292.68µg / dl). While the mint worked to reduce this rate (64.62 µg / dl at 2 % and 90.09 µg / dl at 4%) and parsley also had a positive effect in reducing the ratio of lead in rats blood to (94.14 µg / dl at 2%) and (95.58 at 4%). The effect of lead on a group of liver enzymes Alkaline Phosphatase was also studied. Rats feeding on lead led to an increase in the ratio of this enzyme from the normal level (73.8 IU / L) to a high level (197.8 IU / L), while the medicinal plants used within the current study From this effect, the mint worked to limit this rise to (Mint with 2% concentration 82.1 IU / L). As for the other mint concentration and parsley concentrations, it converged in the positive effect in reducing the lead effect to (Parsley with 2% concentration 88.4 IU / L) (Parsley with 4% concentration 86.2 IU / L), (Mint with 4% concentration 115 IU / L), As for (aspartate aminotransferase), lead had a negative effect on this enzyme, leading to a high level in the blood (lead (positive control) 242.8 U / l) compared to the standard group fodd (negative control) 91 U / l), so we find it through The current study shows that the best plants with a concentration of (Mint with 2% concentration 131.8 U / l) from the talk of reducing the effect of negative lead on this enzyme follows it in terms of preference (Parsley with 4% concentration 123.8 U / l), (Parsley with 2% concentration 121.6 U / l) and (Mint with 4% concentration 106.8 U / l). Also, the effect of these plant concentrations has been studied in reducing the negative effect of lead on the liver enzyme Alanine Transaminase where the effect of lead was evident by raising the concentration of this enzyme in the blood Rats from (negative control) 36 U / l) to (lead (positive control) 144 U / l), while the best treatment in terms of the positive effect on the enzyme (Mint with 2% concentration 38.2 U / l) came after it where I preferred the results (Parsley with 4% concentration 46 U / l), (Mint with 4% concentration 46.8 U / l), (Parsley with 2% concentration 48 U / l), respectively. The results of the study also indicated the negative effects on the weights of the internal organs of the rats (the subject of the study), as they led to an increase in the weight of the liver and kidneys and a decrease in the weight of the testicles. Mint with a concentration of (2%) worked to reduce the weight gain of the liver and kidneys resulting from lead poisoning. It also worked to reduce weight loss in the testicles, as it is closest to the normal weights of rat that were not fed lead, followed by the other concentration of mint (4%) Parsley with all concentrations (2% - 4%) in terms of preference, respectively. We conclude from the current study that the best treatment for lead poisoning among the variables studied is mint with a concentration (2%). Where mint (2%) distinguished in all results from the studies concentrations.