أحمد مهدي مالك المشهدي

This study aimed to evaluate the hematoprotective effects of eugenol against iron overload in male rats. A total of 30 rats were randomly divided into six equal groups as follows: the control negative (C-) group I.P injection distal water. The control positive (C+) group received iron dextran (100 mg/kg-BW) I.P injection. The IE1 and IE2 groups received iron dextran 100 mg/kg-BW I.P and eugenol (50,100 mg/kg-BW) orally, respectively, and the E3 and E4 groups received eugenol (50,100 mg/kg-BW) orally. After 30 days of the experiment, the blood was collected to measure the experimental parameters. The results demonstrated a significant increase in RBCs, Hb percentage, WBCs, PCV, and PTL in the C+ group compared to the C- group. Also, there was a non-significant difference between IE1 and C+ in RBCs and Hb. Meanwhile, PCV decreased significantly in IE1 compared with C+. Conversely, the C+ group showed decreased MCV compared with IE1. Microscopic examination of blood smears indicated normal red blood cell morphology in the C- and iron dextran with eugenol-treated groups, while the C+ group exhibited microcytic hypochromic morphology. In conclusion, the ameliorative effect of eugenol against iron overload-induced hematotoxicity is achieved by restoring the hematological parameters near the normal control.

تاثير سمية علاج الميتاكلوربرمايد على الكبد والكلية في القطط واعطاء الجرعة الامنة من العلاج وحصل البحث على المراكز الاولى من كلية الطب البيطري وجامعة الكوفة.

طرق الحقن السيطرة على الحيوان تجريع الحيوان وتخديرة