أ.م. د. أفاق جابر كاظم النجم

Nano applications are among the most important characteristics that characterize materials science and have entered into chemistry in all its fields. Nano properties are what distinguish the efficiency of any material. We have studied the nano-scale behavior of a compound through a microscopic microscope. Palladium is ailing riveted by the anthropological body once gulped. Plants such as the liquid hyacinth die. Great quantities of palladium can be lethal., Palladium is a bright silvery white metal from the platinum group, but it is less dense than all the metals in this group. It was discovered in 1803 by the scientist and chemist William Hyde and Laston. Palladium does not react with oxygen in the atmosphere, so it is quite stable, but it is soluble in water at room temperature and in some acids under certain conditions. The reputation of cramming the living helpfulness of a integer of equipped complexes encompassing diverse collections of compensators, which may have an bearing in the biotic arena or the manufacturing pitch. Where it is used in the manufacture of many medical equipment and tools used in the field of medicine, such as surgical tools and tools used in the field of dentistry., Also use it to filter and purify water from hydrogen., Where palladium metal can filter more than 90% of the proportion of hydrogen in hydrogen elements such as water. It is more widely used in the purification and purification of water from wells and springs from hydrogen and extraneous pollutants. Keywords: bio compound, bio ligand, bio complex.

This search designed new series complexes of (Mn , Fe, Co, Ni, Cu, and Pd)(II) ,which prepared from Chalcone - Azo derived contained Paracetamol . The results illustrate that, the mole ratio (ligand : metal) (2:1) for all complexes and the geometric shapes of complexes were an Octahedral except Pd(II) complex was Square planer. the complexes characterized by ( UV-Visible, FTIR, C.H.N, Electrical molar conductivity and Magnetic susceptibility). This ligand coordinated with metal ions via (N) atom of Azo group and (O) atom of OH group of Paracetamol , the biological examination tested Pd(II)complex as antitumor Thyroid cancer cells(FTC-133) and compered it with healthy cells to evaluate the possibility of using it as therapeutic method. In addition , it tested Cu(II) and Ni(II) complexes as antimicrobial activity towards two types of Gram negative and Gram positive bacteria

New mixed azo imidazole ligand complexes of Ni(II), Cu(II), Cd(II) and Hg(II) were prepared using (E)-2-((4- chloro phenyl)diazenyl)-4,5-bis(4-methoxy phenyl)-1H-imidazole (CPDMI) as a primary ligand and (E)-2-((4- bromo phenyl)diazenyl)- 4,5-bis(4-methoxy phenyl)-1H-imidazole (BPDMI) as a secondary ligand, the general formula for all ions was [M(L1L2Cl2)]. H2O. The prepared metal ion complexes were characterized by FT-IR, UV‒Vis spectrophotometric, 1H-NMR, mass spectral analysis, molar conductivity, and magnetic moment techniques. Based on the obtained data, the suggested molecular structure of all the metal complexes is octahedral geometry. The biological activity of the free ligands and their Ni(II) and Hg(II) complexes has also been studied. The molecular docking study was employed to predict and optimize the antibacterial outcomes, and a satisfactory concurrence between experimental and theoretical results was observed.

This paper explained synthesis of new ligand 1-(4-((4,5-bis (4-methoxy phenyl)-1H-imidazol-2-yl)diazenyl)phenyl)-3- (4-bromophenyl)prop-2-en-1-one (LBr), this ligand coordinates with (Co, Ni, Cu, Zn, Hg and Pd)(II) in mole ratio (1:2), the ligand characterized by numerous spectroscopic techniques such (UV-Visible, H-NMR, Mass, IR, C.H.N), while its complexes characterized by (UV-Visible, IR, C.H.N., electrical molar conductivity and magnetic susceptibility). The results of this study proposed an Octahedral geometry for all complexes excepting Pd(II) complex was square planer antitumor activity against breast cancer line (MCF-7) was gauged using Pd(II)complex, which has been shown selective cytotoxicity destroying cancer cells, this decides Pd(II) complex could be used to create anti-cancer medication in the forthcoming after compered between ligand has been prepared and this complex in cytotoxic effects.

Abstract A new series of mixed ligand complexes synthesized and characterized using of azo ligand derived from (5-methyl— imidazole) with (8-hydroxy quinolone). New mix-ligand structures and their transitional metal complexes were fully characterized using several techniques, including molar conductance, elemental analysis (C.H.N), electronic spectral, magnetic measurements, 1HNMR, spectral studies, and mass spectra. The data shows that these complexes have a composition of [ML(8-HQ) Cl2] H2O where M = Co(II), Zn(II), Cu(II), X=0, and Ni(II), X=1, [ML(8-HQ)] Cl. where M=Pd. The electronic spectral data and magnetic susceptibility calculations of the complexes indicate that the octahedral geometry of all complexes, except for the Pd(II) complex, indicates a planar-square geometry. The results demonstrate that the nitrogen of the imidazole ring and azo nitrogen atom of the primary ligand are coordination sites with a nitrogen atom and oxygen atom of a secondary ligand of the (8-HQ) in the basic medium. Biological effects of the palladium (II) complex are screening against human breast cancer (MCF-7 and AMJ-13) and normal cells (HBL) were examined, which indicated colon cancer cell line LS-174. The results show the highest activity effect for the complex.

The complexes of Co (II), Ni (II), Cu (II), Zn (II), Cd (II), Pt (II), and Au (III) were prepared from the complexation reaction between the new Schiff base ligand and metal ions. This ligand(3,4-bis(((E)-1-(2-(((E)-(3-hydroxy-5-(hydroxymethyl)- 2-methylpyridin-4-yl) methylene) amino) phenyl) ethylidene) amino) phenyl) phenyl) methanone was derived from the condensation reaction of 3,4-diamino benzophenone, 2-amino acetophenone, and pyridoxal hydrochloride. The ligand and its complexes were characterized by C.H.N elemental analysis, Uv-Vis, FT-IR, 1H-NMR and molar conductivity, Atomic absorption, magnetic moment measurements and mass spectra studies. The results of this studies show the coordination sites for the ligand with the metal ion were to be through oxygen of the hydroxyl group, and the nitrogen of azomethine groups. The electronic spectral and magnetic measurement data predict octahedral structure of the complexes, except for Pt (II) and Au (III) complexes were suggested a square planar geometry. All complexes show that nonelectrolytes properties, but Pt (II) and Au (III) complexes are electrolyte nature. New Schiff base ligand and its metal complexes were Screened against bacterial and fungal strains and their preliminary results compounds exhibited the high effect of activity. This may be attributed to the impact of both the chelate effect of new Schiff bases ligand and the role of the metal in these complexes.

حاصلة على لقب أستاذ مساعد في أيلول 2020

تمت مناقشة الدكتوراه في 23/2/2020

أكملت الدكتوراه في 2020