Benner
الدكتور شيماء عبدالحسين شلاش ( أستاذ مساعد )
كلية الصيدلة - صيدلة عام
[email protected]
 
 
 
Pathological study for effect of alcoholic extraction of Nigella sativa on inffected rabbits with Fasciola gigantica.
تحميل
بحث النوع:
علوم التخصص العام:
Shaimaa Abdul Hussein Shlash اسم الناشر:
Jassem Hameed AL-Kuzaai اسماء المساعدين:
Al-Kufa University Journal for Biology الجهة الناشرة:
VOL.7No.1 ISSN:2311-6544  
2015 سنة النشر:

الخلاصة

This study included of effect alcoholic extract of Nigella sativa seeds on Fasciola gigantica parasite used (24) adult rabbits which distributed randomly into four equal groups and give doses (200,400,600 mg / kg) and control group of body weight , after end of experiment was drugg and the blood drawing directly from heart to conducting immunologic tests (Total count of Red blood cells, Haematocrit value, Estimating concentration Hemoglobin, Total count of White blood cells and Differential count of White blood cells) and then the animals dissected and eradication of the liver, spleen and kidney for the preparation of tissue sections. Results refer there are not significant difference of alcoholic extract of Nigella sativa seeds at level (P<0.05) in blood components of healthy animals while in infected animals and treated there are less significant effect when compared with the infected animals only which appeared increase significant in the count of White blood cells and significant decrease in the count of Red blood cell and Haematocrit value and amount of Hemoglobin. Also this results showed the ability of alcoholic extract of Nigella sativa seeds at dose (600 mg/kg) Was more effective in reducing the numbers of worms F.gigantica in infected rabbits when compared with the untreated animals