الخلاصة

During the period between the beginning of February 2016 and the end of October 2017, 60 individuals were enrolled in the present work. In the Center of Oncology for Hematology of Al-Hussein Medical City in Karbala, Iraq, 30 sera samples from patients with ALL who had no family history of cancer were collected, before receiving chemotherapy. The statistical analysis using the student's t-test showed significant differences (p = 0.000 for lectin and p = 0.005 for MDA) when the two study groups (patients with ALL and healthy individuals) compared together. The study showed a statistically significant increase (p = 0.005) in male patients with ALL compared with their corresponding males in the control group. This finding was consistent with the results of comparing lectin levels in female patients with the control group (p = 0.019), while no significant differences were observed in CLEC4E levels when the intra-subgroups compared, separately. The highest concentration and activity (36.062 g / L and 168,660 U / L) of Ceruloplasmin Oxidase were recorded in the samples of females with ALL. The study Results showed that this type of lectin is naturally produced in humans, but its levels are elevated when the incidence of ALL, where the study recorded a rise in CLEC4E levels in 26 of the 30 resident samples (sensitivity 87%), in addition, It has been found that the levels of this protein increase with the progressive of cancer.The study showed decrease in the serum CLEC4E levels at 80% of patients with ALL after treated with chemotherapy. The sensitivity of the evaluated lectin in the sera samples of patients with ALL reached to 100% when the levels of lectin were combined to the levels of MDA.