Benner
نادية صادق البوعبيد ( أستاذ مساعد )
كلية التربية للبنات - الكيمياء
[email protected]
07803957933
 
 
 
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF SOME NEW HETEROCYCLIC COMPOUNDS DERIVED FROM 4- AMINOACETOPHENONE
تحميل
بحث النوع:
علوم التخصص العام:
نادية صادق مجيد اسم الناشر:
حنان فالح محسن رضية عبد الباقي خضر اسماء المساعدين:
Biochem. Cell. Arch. الجهة الناشرة:
Vol. 18, Supplement 1, pp. 1107-1116, 2018  
2018 سنة النشر:

الخلاصة

Our work aimed for organic synthesis and biological investigation of some new heterocyclic derivatives by three steps : the first step included synthesis of some five-membered and six-membered heterocyclic derivatives (Pyrazole, Isoxazole, Oxazine and Thiazine) from Chalcone. The second step included synthesis of some 1,3-Oxazipene derivatives from Schiff’s bases derived from Azo compound. The third step included the assay of biological activity of all compounds against four types of pathogens bacteria (Staphylococcus aureus, Granutice tella adiacens) gram positive and ( E. coli, Proteus mirabilis) gram negative the results exhibited excellent biological activity for all derivatives compared to antibiotics (Ampicillin and Ciprofloxacin). These compounds were identified and confirmed by FT- IR, 1HNMR, 13CNMR and elemental analysis.