الخلاصة

Multiple resistances to antimicrobial drugs arising in Escherichia coli isolates may complicate therapeutic management of urinary tract infection (UTI) by this organism. In order to assess the multidrug resistance (MDR) among urinary E. coli isolates, we have tested 27 antimicrobial drugs against 192 isolates from patients with significant bacteriurea from 3 hospitals in Najaf during june to Augest 2011. The number of patients with urinary tracts infection was higher in females, 136 (70.9%) compared to males, 56 (29.1%). The antibiotic susceptibility patterns of isolates were determined by disk diffusion method. Among the isolates from the hospital patients, 95.3%, 94.3%, 93,8%, 92.2%, 91.7%, and 90.1% were resistant to carpencillin, ticarcillin, ampicillin, cefepim, cefamandol, and pipracillin, respectively; Resistant profile for cefoxitin, and amoxicillin was 85.4% and 80.2%, respectively. Uoropathogenic E. coli was resistant to cefotaxime, cefetriaxon, and Aztreonam (71.4%), and resistance to trimetheoprim, doxicycllin, ceftazidim, amoxiclave, and nalidixic acid were 69.8%, 68.2%, 68.8%, 67.2%, and 61%, respectively. susceptibility prfile to aminoglycosid antibiotics (tobramycin, gentamycin, and amikacin) were 56.8%, 53.1%, and 10.4%, respectively. And for fluoroquinolons (ciprofloxacin, norfloxacin, ofloxacin, and levofloxacin) were 49%, but for gatifloxacin, resistant was 40.6%. E. coli was resistance to chloramphenicol and nitroforantoin 17.7% and 12%, respectively.The high prevalence of drug resistance among UTI patients calls for continuous surveillance to assure effective control of this infection.