Benner
حيدر مهدي العارضي ( أستاذ مساعد )
كلية الطب - جراحة عامة
[email protected]
07801637012
 
 
 
RoleofTrospiumchlorideandtamsulosintherapyfortreatingpatientswithsymptomsofover-activebladderrelatedtobenignprostaticenlargement
تحميل
بحث النوع:
طب التخصص العام:
FalahMahdiAli اسم الناشر:
HayderMahdiAlaridy اسماء المساعدين:
INTERNATIONALJOURNALOFRESEARCHINPHARMACEUTICALSCIENCES الجهة الناشرة:
INTERNATIONALJOURNALOFRESEARCHINPHARMACEUTICALSCIENCES  
2020,11(1) سنة النشر:

الخلاصة

ABSTRACTToassessthebeneθitandsafetyofcompositetherapy(TamsulosinandTro-spiumdrugs)intreatingbenignprostaticenlargementcomplain,mainlyover-activeurinarybladdersymptoms. OBJECTIVE:Thestudyhasbeendesignedto estimate the beneθit and safety of Trospium and Tamsulosin in pro-cessing of symptoms of excessive bladder and benign prostate hyperplasia(BPH). Patients and Methods: Prospective clinical trial study conducted atAl-Diwaniyateachinghospitalsandprivateclinicsfrommarch2016tomarch2017,topatientsBPHandbothersomesymptoms. 60patientsweretreatedwithTamsulocinand60patientsweretreatedbyTamsulocinandTrospium.RESULTS:MedianscoresofIPSS,OABSS,andQOLprovednobigdifferencebetweentwostudysetsbeforestaringtreatment(P=0.544),(P=0.287),(P=0.668)consecutively. Afteronemonth,bothtreatmentsledtoabigreduc-tioninIPSS,OABSSmedianscore;(P<0.001),(P<0.001). Followingthreemonths,bothtreatmentsresultedinsigniθicantreductioninIPSS(P<0.001),OABSS(P<0.001),QOLresult,(P<0.001)consecutively. Conclusion: TheseresultssuggestwhichtreatmentwithTrospiumandtamsulosintherapypro-videsbeneθitformenwithnatural-Syndromeoftheacuteurinarytractandbenignenlargedprostate.