Benner
فلاح شريف الخفاجي ( أستاذ )
كلية الصيدلة - صيدلة عام ( رئيس القسم )
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The pH effect on Polarographic Potential wave of Carvediolol, Atenolol and Propranolol
تحميل
بحث النوع:
علوم التخصص العام:
Oraas Adnan Hatem*1 اسم الناشر:
Falah Shareef Abed Suhail2, Amer Mousa Juda3 اسماء المساعدين:
October - December 2016 - JCPS Volume 9 Issue 4 الجهة الناشرة:
ISSN: 0974-2115 www.jchps.com  
2016 سنة النشر:

الخلاصة

Reduction potential for carvedilol, atenolol and Propranolol was determined by polarographic style used. Hanging Mercury Dropping Electrode (HMDE), all these pharmaceutical compounds was electro active with half wave potential E1/2 of 0.148, 0.112 and 0.118 V respectively, PH effect on the polarographic potential wave was study in phosphate buffer solution with a concentration of 0.98×10-5, 1.12×10-5 and 1.15×10-5 M for carvedilol, atenolol and Propranolol respectively, the values of pH ranged at 5, 6, 7.4, 8. The result showed that the values of half wave potential E1/2 inversely proportional with pH and diffusion current (id) is directly proportional.