Benner
دنيا لفته الدحيدحاوي ( أستاذ مساعد )
كلية الصيدلة - صيدلة عام
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NOVEL ANTIOXIDANTS COMPOUNDS DERIVED FROM ISATINE
تحميل
بحث النوع:
صيدلة التخصص العام:
Dunya AL-Duhaidahawi اسم الناشر:
Majid S. Jabir, Ahmed A. Al-Amiery, Ahmed E. Abdel Moneim, Ayad F. Alkaim and Abdul Amir H. Kadhum6 اسماء المساعدين:
BIOCHEMICAL AND CELLULAR ARCHIVES الجهة الناشرة:
scopus  
2018 سنة النشر:

الخلاصة

ABSTRACT : Isatin was first synthesized in 1841 by Erdmann and Laurent by the oxition reaction of indigo dye by an oxiizing agent nitric acid/chromic acid. It was found in many plants, like Isatis tinctoria, Calanthe discolor and in cannonball tree. Isatin- azomethine had been studied for their important medicinal applications.The syntheses of Isatin- azomethines, that are quite compulsory pharmaceutical properties because of their structurally motivating antioxidant activities. Isatin - azomethines had been synthesized effectively via the reaction of Isatinwithvarious amins. Various spectroscopicaltechniqes were used to characterized the synthesized Isatins. The antioxidant capacity of Isatin-azomethines were predestined by representative spectroscopically techniques, employing radical’s DPPH (2,2-diphenyl-1- picrylhydrazyl), FRAP (Ferric Reducing Antioxidant Power) and Ferrous ions chelating activity assays compared to that of ascorbic acid. Isatin-azomethines displayed an superior scavenging activities paralleled to the ascorbic acid.