الخلاصة

Breast cancer is a malignant tumor arising from the terminal duct lobular unit of the breast tissues. It is most prevalent malignancy in women and its incidence is increasing globally and the lifetime risk of developing breast cancer between 5-10%. Tumor suppressor geneTP53 is essential for preventing inappropriate cell proliferation and maintaining genome stability and integrity following genotoxic stress. TP53 gene is the most commonly mutated gene in cancer and approximately 20% of breast cancer. Thus, gene expression was investigated.