Benner
احمد وحيد الحسناوي ( مدرس مساعد )
كلية الصيدلة - صيدلة عام
[email protected]
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Synthesis, characterization and evaluation of antibacterial activity of some new derivatives of Veronal
بحث النوع:
صيدلة التخصص العام:
Ahmed W.Radhi اسم الناشر:
اسماء المساعدين:
Der Pharmacia Lettre, الجهة الناشرة:
2016, 8 (19):450-456  
2016 سنة النشر:

الخلاصة

ABSTRACT Reaction of veronal with acetic anhydride gave N,N-1,3-diacetyl veronal(As)which was reacted with some aromatic aldehydes to give chalcones(ch1-ch7). Sulphadiazineconverted to diazonum salt will be reacted with sodium azide and sodium acetate to form 4-azido-N-(pyrimidin-2-yl)phenylsulfonamid(Az).1,2,3-triazoline derivatives (T1-T7) were prepared by cycloaddition reactions between compound (Az) with chalcones. All compounds were characterized by C.H.N.S. analyses , F.T.I.R spectra and 1H-NMR spectrum. Some of the prepared compounds were screened for antibacterial activity.