Benner
احمد وحيد الحسناوي ( مدرس مساعد )
كلية الصيدلة - صيدلة عام
[email protected]
07810742409
 
 
 
Characterization, Synthesis and Study of Biological Activity of new Derivatives of Sulphadiazine
بحث النوع:
صيدلة التخصص العام:
1Ezat H. Zmam, اسم الناشر:
2Ahmed W. Radh, 3 Farked W. Salman اسماء المساعدين:
International Journal of ChemTech Research الجهة الناشرة:
CODEN (USA): IJCRGG, ISSN: 0974-4290, ISSN(Online):2455-9555 Vol.10 No.4, pp 89-96, 2017  
2017 سنة النشر:

الخلاصة

Abstract : Sulphadiazine converted to 2-chloro-N-(4-(N-pyrimidin-2-yl sulfamoyl) phenyl) acetamide (A) as a result of reacation through chloroacetyl chloride is going to be responded through sodium azide towards form 2-azido-N-(4-(N-pyrimidin-2-yl-sulfamoyl) phenyl acetamide (B). 1,2,3-triazoline derivatives (S1-S7) were made through cycloaddition responses among substance (B) which includes chalcones. Ready substances were being stamped by T.L.C. , C.H.N.S. explanations, F.T.I.R spectra together with 1H-NMR range. 1,2,3-triazoline derivatives were checked for antibacterial activity. Keywords : 1,2,3-triazoline, azide,anti bacterial activityandSulphadiazine